Association between different diet quality scores and depression risk: the REGICOR population-based cohort study.

Autor: Lugon G; Epidemiology and Public Health Programme, Hospital del Mar Medical Research Institute, PRBB, Carrer Doctor Aiguader 88, Barcelona, 08003, Spain. gabrielamaria.lugon.ceruti@psmar.cat.; Preventive Medicine and Public Health Training Unit PSMar-UPF-ASPB (Parc de Salut Mar - Pompeu Fabra University - Agència de Salut Pública de Barcelona), Barcelona, Spain. gabrielamaria.lugon.ceruti@psmar.cat.; PhD Program in Biomedicine, Universitat Pompeu Fabra (UPF), Barcelona, Spain. gabrielamaria.lugon.ceruti@psmar.cat., Hernáez Á; Epidemiology and Public Health Programme, Hospital del Mar Medical Research Institute, PRBB, Carrer Doctor Aiguader 88, Barcelona, 08003, Spain.; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Facultat de Ciènces de la Salut Blanquerna, Universitat Ramon Llull, Barcelona, Spain.; Consortium for Biomedical Research - Cardiovascular Diseases (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain., Jacka FN; School of Medicine, Food & Mood Centre, IMPACT Strategic Research Centre, Deakin University, Melbourne, VIC, Australia., Marrugat J; Epidemiology and Public Health Programme, Hospital del Mar Medical Research Institute, PRBB, Carrer Doctor Aiguader 88, Barcelona, 08003, Spain.; Consortium for Biomedical Research - Cardiovascular Diseases (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain., Ramos R; Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Girona, Spain.; Girona Biomedical Research Institute (IdIBGi), Dr. Josep Trueta University Hospital, Girona, Spain.; Department of Medical Sciences, School of Medicine, University of Girona, Girona, Spain., Garre-Olmo J; Girona Biomedical Research Institute (IdIBGi), Dr. Josep Trueta University Hospital, Girona, Spain.; Serra-Húnter Professor Department of Nursing, University of Girona, Girona, Spain., Elosua R; Epidemiology and Public Health Programme, Hospital del Mar Medical Research Institute, PRBB, Carrer Doctor Aiguader 88, Barcelona, 08003, Spain.; Consortium for Biomedical Research - Cardiovascular Diseases (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.; Faculty of Medicine, University of Vic - Central University of Catalunya, Vic, Spain., Lassale C; Epidemiology and Public Health Programme, Hospital del Mar Medical Research Institute, PRBB, Carrer Doctor Aiguader 88, Barcelona, 08003, Spain. camille.lassale@isglobal.org.; Consortium for Biomedical Research - Pathophysiology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. camille.lassale@isglobal.org.; ISGlobal, Barcelona, Spain. camille.lassale@isglobal.org.; Universitat Pompeu Fabra (UPF), Barcelona, Spain. camille.lassale@isglobal.org.
Jazyk: angličtina
Zdroj: European journal of nutrition [Eur J Nutr] 2024 Dec; Vol. 63 (8), pp. 2885-2895. Date of Electronic Publication: 2024 Aug 24.
DOI: 10.1007/s00394-024-03466-z
Abstrakt: Background: Our aim was to determine the association between diet quality and depression incidence in the population-based REGICOR cohort study, Catalonia, Spain.
Methods: Prospective observational study using participants' baseline (2003-2006), follow-up (2007-2013) and clinical records data. Five diet quality scores were derived from a food frequency questionnaire (FFQ) at baseline: the relative Mediterranean Diet Score (rMED), the Modified Mediterranean Diet Score (ModMDS), a Dietary Approaches to Stop Hypertension (DASH) score, a Healthful Plant-based Diet Index (HPDI) and the World Health Organization Healthy Diet Indicator (WHO-HDI). Participants using pharmacological antidepressant treatment were excluded as a proxy for presence of depression at baseline. At follow-up, the Patient Health Questionnaire (PHQ-9) was applied to assess depressive symptoms (≥ 10 defining depressive disorder). A secondary outcome was depression diagnosis assessed through clinical records. Logistic regression and Cox proportional hazards models were used.
Results: Main analysis included 3046 adults (50.3% women) with a mean age of 54.7 (SD = 11.6) years. After 6-years follow-up, 184 (6.04%) cases of depressive disorder were identified. There was 16% lower odds of depressive disorder per 1SD increase of rMED (OR = 0.84; 95%CI = 0.71-0.98). Secondary outcome analysis (n = 4789) identified 261 (5.45%) incident cases of clinical depression diagnosis over 12 years follow-up, and 19% lower risk of clinical depression was observed with the WHO-HDI (HR = 0.81; 95%CI = 0.70-0.93). Adjusting for BMI did not attenuate the findings.
Conclusions: A significant inverse association between diet quality and depression incidence was found in this population-based cohort study, independent of sociodemographic, health and lifestyle. Adherence to a healthy diet could be a complementary intervention for the prevention of depression.
(© 2024. The Author(s).)
Databáze: MEDLINE
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