Gastrointestinal Alpha Heavy Chain Disease With Persistent Campylobacter Jejuni Colonization and Refractory Giardiasis.
| Autor: | Tang W; Department of Internal Medicine, New York Medical College, Valhalla, NY., Lin Z; Department of Gastroenterology and Hepatobiliary Diseases, New York Medical College, Valhalla, NY., Sharma P; Department of Internal Medicine, New York Medical College, Valhalla, NY., Heering G; Department of Internal Medicine, New York Medical College, Valhalla, NY., Dworkin B; Department of Gastroenterology and Hepatobiliary Diseases, New York Medical College, Valhalla, NY., Steinberg A; Department of Hematology and Oncology, New York Medical College, Valhalla, NY., Shakil F; Department of Pathology, New York Medical College, Valhalla, NY., Schorr-Lesnick B; Department of Gastroenterology and Hepatobiliary Diseases, New York Medical College, Valhalla, NY. |
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| Jazyk: | angličtina |
| Zdroj: | ACG case reports journal [ACG Case Rep J] 2024 Aug 22; Vol. 11 (8), pp. e01467. Date of Electronic Publication: 2024 Aug 22 (Print Publication: 2024). |
| DOI: | 10.14309/crj.0000000000001467 |
| Abstrakt: | Alpha heavy chain disease (αHCD) is a rare variant of the mucosa-associated lymphoid tissue lymphoma characterized by expression of a monotypic truncated immunoglobulin α heavy chain. αHCD frequently involves the gastrointestinal (GI) tract, and its pathogenesis has been linked to clonal B-cell expansion from chronic immune stimulation by infectious agents. We report a rare case of GI αHCD with 5 concomitant pathogens identified on a GI multiplex real-time polymerase chain reaction panel, featured by persistent Campylobacter jejuni colonization and refractory giardiasis. (© 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.) |
| Databáze: | MEDLINE |
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