Ongoing and future clinical trials of device therapies for patients with heart failure.

Autor: Khalid SN; Department of Internal Medicine, SUNY Upstate Medical University., Mansoor T; Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine. Electronic address: taha.mansoor@wmed.edu., Bilal MI; Department of Internal Medicine, Allegheny Health Network., Ijaz SH; Division of Cardiology, Hartford Hospital CT, USA., Fudim M; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Greene SJ; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Nambi V; Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA; Michael E. DeBakey Veterans Affair Medical Center., Virani SS; Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA; Department of Medicine, Aga Khan University, Karachi; Texas Heart Institute, Houston, TX, Pakistan., Fonarow GC; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles CA, USA., Abramov D; Division of Cardiology, Department of Medicine, Loma Linda University Health, Loma Linda, CA, USA., Minhas AMK; Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Nov; Vol. 49 (11), pp. 102805. Date of Electronic Publication: 2024 Aug 17.
DOI: 10.1016/j.cpcardiol.2024.102805
Abstrakt: Heart failure continues to pose a significant burden in terms of morbidity, mortality, and healthcare costs worldwide despite the implementation of guideline-directed medical therapy. Addressing this challenge and improving clinical outcomes for this patient population remains an urgent priority. Recognizing the limitations in current medical approaches and exploring strategies to overcome these limitations are crucial steps toward improving future outcomes. Various device-based interventions, such as Cardiac Resynchronization Therapy devices and Left Ventricular Assist Devices, have demonstrated notable benefits for individuals with heart failure. Our review is aimed at summarizing the ongoing research into new device therapies for heart failure, emphasizing their potential to overcome the current challenges in treatment. By utilizing Clinicaltrials.gov, an online repository, we conducted a comprehensive search for trials investigating emerging device therapies for patients dealing with heart failure.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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