Differential neural mechanisms for movement adaptations following neuromuscular training in young female athletes with a history of sports-related concussion.

Autor: Zuleger TM; Emory Sports Performance And Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH, USA. Electronic address: Taylor.zuleger@emory.edu., Slutsky-Ganesh AB; Emory Sports Performance And Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; Department of Kinesiology, University of North Carolina at Greensboro, Greensboro, NC, USA., Kim H; Ohio Musculoskeletal & Neurological Institute, Ohio University, Athens, OH, USA., Anand M; Emory Sports Performance And Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; Department of Mechanical Engineering, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India., Warren SM; Emory Sports Performance And Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA., Grooms DR; Ohio Musculoskeletal & Neurological Institute, Ohio University, Athens, OH, USA; Division of Athletic Training, School of Applied Health Sciences and Wellness, College of Health Sciences and Professions, Ohio University, Athens, OH, USA; Division of Physical Therapy, School of Rehabilitation and Communication Sciences, College of Health Science and Professions, Ohio University, Grover Center, Athens, OH, USA., Yuan W; Pediatric Neuroimaging Research Consortium, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Riley MA; Department of Rehabilitation, Exercise, & Nutrition Sciences, University of Cincinnati, Cincinnati, OH, USA; Human Performance & Neuromechanics Lab, University of Cincinnati Digital Futures, Cincinnati, OH, USA., Gore RK; Shepherd Center, Atlanta, GA, USA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Myer GD; Emory Sports Performance And Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; The Micheli Center for Sports Injury Prevention, Waltham, MA, USA; Youth Physical Development Centre, Cardiff Metropolitan University, Wales, UK., Diekfuss JA; Emory Sports Performance And Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA.
Jazyk: angličtina
Zdroj: Neuroscience [Neuroscience] 2024 Oct 18; Vol. 558, pp. 70-80. Date of Electronic Publication: 2024 Aug 17.
DOI: 10.1016/j.neuroscience.2024.08.014
Abstrakt: Sports-related concussion (SRC) in adolescent athletes is associated with an increased risk of subsequent lower extremity injury. Neuromuscular training (NMT) has shown promise for reducing lower extremity injuries following SRC, however, neural adaptations in response to changes in lower extremity biomechanics following NMT in athletes with a history of SRC (HxSRC) remains poorly understood. Therefore, the purpose of this study was to identify changes in neural activity associated with lower extremity movement adaptations following a six-week NMT intervention in athletes with a HxSRC. Thirty-two right-hand/foot-dominant female adolescent athletes (16 with self-reported HxSRC, 16 age- and anthropometrically-matched controls) completed a bilateral leg press task with 3D motion analysis during functional magnetic resonance imaging (fMRI). Movement adaptations were defined as a change in frontal and sagittal plane range of motion (ROM) during the fMRI bilateral leg press task. Significant pre- to post-NMT reductions were observed in the non-dominant (left) mean frontal plane ROM. Whole-brain neural correlate analysis revealed that increased cerebellar activity was significantly associated with reduced mean left-knee frontal ROM for matched controls. Exploratory within group analyses identified neural correlates in the postcentral gyrus for the HxSRC group which was associated with reduced mean left-knee frontal plane ROM. These distinct longitudinal changes provide preliminary evidence of differential neural activity associated with NMT to support knee frontal plane control in athletes with and without a HxSRC.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Gregory D. Myer has consulted with Commercial entities to support application to the US Food and Drug Administration but has no financial interest in the commercialization of the products. Dr. Myer’s institution receives current and ongoing grant funding from National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases Grants U01AR067997, R01 AR070474, R01AR055563, R01AR076153, R01 AR077248 and has received industry sponsored research funding related to brain injury prevention and assessment with Q30 Innovations, LLC, and ElMinda, Ltd. Dr. Myer receives author royalties from Human Kinetics and Wolters Kluwer. Dr. Myer is an inventor of biofeedback technologies (2017 Non-Provisional Patent Pending- Augmented and Virtual reality for Sport Performance and Injury Prevention Application filed 11/10/2016 (62/420,119), Software Copyrighted.) designed to enhance rehabilitation and prevent injuries and receives licensing royalties. Dr. Myer and Dr. Diekfuss receive inventor-related royalties resultant from biofeedback technologies (Include Health: LIC1907082014-0706). Dr. Grooms has current and ongoing funding support from the National Institutes of Health/National Center for Complementary and Integrative Health (R21 AT009339-02) and National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR076153, R01AR077248) and the US Department of Defense Congressionally Directed Medical Research Program Peer Reviewed Orthopaedic Research Program (OR170266), research award (81XWH-18-1-0707). Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the Department of Defense. Dr. Diekfuss also receives author royalties from Kendall Hunt Publishing Company.
(Copyright © 2024 International Brain Research Organization (IBRO). Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: