Relationship between Exhaled Aerosol and Carbon Dioxide Emission Across Respiratory Activities.

Autor: Moseley B; Department of Respiratory Medicine, Royal Brompton Hospital, London SW3 6NP, U.K., Archer J; School of Chemistry, University of Bristol, Bristol BS8 1TS, U.K., Orton CM; Department of Respiratory Medicine, Royal Brompton Hospital, London SW3 6NP, U.K.; Department of Respiratory Medicine, Chelsea & Westminster Hospital, London SW10 9NH, U.K.; National Heart and Lung Institute, Guy Scadding Building, Imperial College London, London SW3 6LY, U.K., Symons HE; School of Chemistry, University of Bristol, Bristol BS8 1TS, U.K., Watson NA; Department of Ear, Nose and Throat Surgery, Guy's & St. Thomas NHS Foundation Trust, London SE1 9RT, U.K., Saccente-Kennedy B; Department of Speech and Language Therapy (ENT), Royal National Ear, Nose and Throat and Eastman Dental Hospitals, University College London Hospitals NHS Foundation Trust, London WC1E 6DG, U.K., Philip KEJ; Department of Respiratory Medicine, Royal Brompton Hospital, London SW3 6NP, U.K.; National Heart and Lung Institute, Guy Scadding Building, Imperial College London, London SW3 6LY, U.K., Hull JH; Department of Respiratory Medicine, Royal Brompton Hospital, London SW3 6NP, U.K.; Institute of Sport, Exercise and Health (ISEH), UCL, London W1T 7HA, U.K., Costello D; Ear, Nose and Throat Department, Wexham Park Hospital, Slough SL2 4HL, U.K., Calder JD; Department of Bioengineering, Imperial College London, London SW7 2AZ, U.K.; Fortius Clinic, London W1H 6EQ, U.K., Shah PL; Department of Respiratory Medicine, Royal Brompton Hospital, London SW3 6NP, U.K.; Department of Respiratory Medicine, Chelsea & Westminster Hospital, London SW10 9NH, U.K.; National Heart and Lung Institute, Guy Scadding Building, Imperial College London, London SW3 6LY, U.K., Bzdek BR; School of Chemistry, University of Bristol, Bristol BS8 1TS, U.K., Reid JP; School of Chemistry, University of Bristol, Bristol BS8 1TS, U.K.
Jazyk: angličtina
Zdroj: Environmental science & technology [Environ Sci Technol] 2024 Aug 13. Date of Electronic Publication: 2024 Aug 13.
DOI: 10.1021/acs.est.4c01717
Abstrakt: Respiratory particles produced during vocalized and nonvocalized activities such as breathing, speaking, and singing serve as a major route for respiratory pathogen transmission. This work reports concomitant measurements of exhaled carbon dioxide volume (VCO 2 ) and minute ventilation (VE), along with exhaled respiratory particles during breathing, exercising, speaking, and singing. Exhaled CO 2 and VE measured across healthy adult participants follow a similar trend to particle number concentration during the nonvocalized exercise activities (breathing at rest, vigorous exercise, and very vigorous exercise). Exhaled CO 2 is strongly correlated with mean particle number ( r = 0.81) and mass ( r = 0.84) emission rates for the nonvocalized exercise activities. However, exhaled CO 2 is poorly correlated with mean particle number ( r = 0.34) and mass ( r = 0.12) emission rates during activities requiring vocalization. These results demonstrate that in most real-world environments vocalization loudness is the main factor controlling respiratory particle emission and exhaled CO 2 is a poor surrogate measure for estimating particle emission during vocalization. Although measurements of indoor CO 2 concentrations provide valuable information about room ventilation, such measurements are poor indicators of respiratory particle concentrations and may significantly underestimate respiratory particle concentrations and disease transmission risk.
Databáze: MEDLINE