Clinical Picture, Diagnosis, Management of NEC, and Effects of Probiotics on its Prevention: A Narrative Review.

Autor:	De Bernardo G; Department of Woman and Child, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy., Carla Z; Division of Pediatrics, Department of Transaltional Medical Sciences, University of Naples Federico II, Naples, Italy., Grazia P; Division of Pediatrics, Department of Transaltional Medical Sciences, University of Naples Federico II, Naples, Italy., Carolina V; University of Naples Federico II Department of Transaltional Medical Sciences Naples Italy., Valentina F; Department of Woman and Child, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy., Simona S; Department of Woman and Child, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy., Maurizio G; Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy., Giuseppe B; University of Siena Department of Molecular and Developmental Medicine Siena Italy., Serafina P; Neonatology Unit, Department of Medicine and Surgery, University of Parma, Pietro Barilla Children's Hospital, Parma, Italy.
Jazyk:	angličtina
Zdroj:	Current pediatric reviews [Curr Pediatr Rev] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08.
DOI:	10.2174/0115733963317134240801113609
Abstrakt:	Preterm newborns represent a population at risk of developing intestinal dysbiosis as well as being predisposed to sepsis and Necrotizing Enterocolitis. Necrotizing Enterocolitis is a condition burdened by many complications and mortality due to an alteration of the intestinal barrier, an immaturity of the immune system, and intestinal dysbiosis. Low gestational age at birth, low birth weight, and early use of antibiotics are other predisposing factors. Instead, breast milk and probiotics are protective factors in providing intestinal homeostasis and microbiome regulation. In this mini-review, we analysed the protective role of probiotics in the onset of Necrotizing Enterocolitis in preterm populations. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Databáze:	MEDLINE
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