| Autor: |
Metanis I; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Simaan N; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel.; Department of Neurology, Ziv Medical Center, Safed 1311001, Israel., Schwartzmann Y; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Jubeh T; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Honig A; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Jubran H; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Magadle J; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Cohen JE; Department of Neurosurgery, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel., Leker RR; Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical medicine [J Clin Med] 2024 Jul 29; Vol. 13 (15). Date of Electronic Publication: 2024 Jul 29. |
| DOI: |
10.3390/jcm13154443 |
| Abstrakt: |
(1) Background : Cervical arterial dissections (CeAD) are a common cause of stroke in young adults. CeAD can be spontaneous (sCeAD) or traumatic (tCeAD). Whether CeAD subtypes differ in clinical, radiological, and outcome characteristics remains unexplored. (2) Methods : Patients with CeAD were identified and divided between sCeAD and tCeAD. Demographics, clinical features, risk factors, imaging findings, treatments, and outcomes were compared between the groups. Logistic regressions were used to determine characteristics associated with favorable outcome. (3) Results : Overall, 154 patients were included (106 sCeAD and 48 tCeAD). Patients with sCeAD were significantly older (mean ± SD 46 ± 12 vs. 35 ± 14, p < 0.001) and were more likely to have hyperlipidemia (19% vs. 4%, p = 0.016), but other risk factors did not differ. Patients with tCeAD less often had signs of early infarction on imaging (21% vs. 49%, p = 0.001) and had lower stroke severity on admission (NIHSS, median, interquartile range [IQR] 0 (0-9) vs. 2 (0-4), p = 0.012), but more often had symptomatic intracranial hemorrhages (12.5% vs. 2%, p = 0.006). Patients with tCeAD less often had favorable outcomes at 90 days (78% vs. 97%, p < 0.001). In the regression analysis, the only variables associated with favorable outcome were age (odds ratio [OR] 1.13, 95% confidence interval [CI] 1.03-1.24), initial stroke severity (OR 0.84, 95% CI 0.73-0.97), degree of vessel stenosis (OR 0.35, 95% CI 0.14-0.83), and involvement of multiple vessels on presentation (OR 0.04, 95% CI 0.02-0.70), whereas dissection subtype was not associated (OR 0.45, 95% CI 0.03-68.80). (4) Conclusions : Dissection subtype is not an independent modifier of the chances of attaining functional independence. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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