Co 2 LASER Therapy as an Option for Non-Healing Surgical Wounds after Radiation Therapy-A Retrospective Study.

Autor: Patil BR; Department of Head and Neck Surgical Oncology, The Karnatak Cancer Therapy and Research Institute, Hubli, Karnataka India., Shikha N; Department of Head and Neck Surgical Oncology, The Karnatak Cancer Therapy and Research Institute, Hubli, Karnataka India.
Jazyk: angličtina
Zdroj: Journal of maxillofacial and oral surgery [J Maxillofac Oral Surg] 2024 Aug; Vol. 23 (4), pp. 953-958. Date of Electronic Publication: 2024 Mar 19.
DOI: 10.1007/s12663-024-02144-1
Abstrakt: Background: Radiation has a huge impact on wound healing with progressive and irreversible impairment at the cellular level, making it very challenging for surgeons in terms of wound healing after salvage surgery in previously radiated patients. CO 2 LASER helps in wound healing by its combined effect yielding a better result. Our study aims to retrospectively evaluate the healing outcome in a series of patients post-radiation, diagnosed with head and neck neoplasm recurrence, undergoing CO 2 LASER treatment for non-healing surgical wounds, post salvage surgery having a previous history of radiotherapy in Head and Neck cancers.
Methodology: A total of seven patients from January 2018 to June 2021 who underwent CO 2 LASER treatment in non-healing surgical wounds, post salvage surgery having a previous history of radiotherapy in Head and Neck cancers were included in this study. Clinical assessment of healing in terms of complete healing, the appearance of the scar, and patient satisfaction, with a follow-up for 18 months.
Results: This series included a total of seven patients, five men and two women, aged between 27 and 62 years with a mean age of 47 years. Three patients had a previous history of radiation, and four patients had a previous history of chemoradiation (CT + RT). Successful healing was noted in all the seven patients. Post-healing all patient's scars were soft, flat, and clinically acceptable. One patient presented with hypopigmentation.
Conclusion: CO 2 LASER therapy speeds up the healing process with minimal discomfort to the patient. CO 2 LASER therapy can be used as an alternative for non-healing surgical wounds after salvage surgery in previously radiated  patients with an unhealthy wound bed where split-thickness skin graft uptake is unpredictable.
Competing Interests: Conflict of InterestNone.
(© The Association of Oral and Maxillofacial Surgeons of India 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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