Impulsivity as a predictor of clinical and psychological outcomes in a naturalistic prospective cohort of subjects at ultra-high risk (UHR) for psychosis from Tunisia.

Autor: Fekih-Romdhane F; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia. Electronic address: feten.fekih@gmail.com., Ghrissi F; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia., Abassi B; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia., Loch AA; Laboratorio de Neurociencias (LIM 27), Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, Brazil; Instituto Nacional de Biomarcadores em Neuropsiquiatria (INBION), Conselho Nacional de Desenvolvimento Cientifico e Tecnológico, Sao Paulo, Brazil., Cherif W; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia., Damak R; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia., Ellini S; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia., Cheour M; The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi hospital, Manouba, 2010 Tunisia; Tunis El Manar University, Faculty of Medicine of Tunis, Tunis, Tunisia., Hallit S; School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon; Applied Science Research Center, Applied Science Private University, Amman, Jordan; Psychology Department, College of Humanities, Effat University, Jeddah 21478, Saudi Arabia. Electronic address: souheilhallit@hotmail.com.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2024 Oct; Vol. 340, pp. 116090. Date of Electronic Publication: 2024 Jul 22.
DOI: 10.1016/j.psychres.2024.116090
Abstrakt: Background: Impulsivity is associated with serious detrimental consequences on physical, mental, behavioral and social aspects of health among patients with psychosis. The present prospective 12-month follow-up study aimed to determine the prevalence of highly impulsive individuals among Ultra High Risk (UHR) patients, how impulsivity evolves over the follow-up period, and whether impulsivity impacts clinical, psychological and functional outcomes in this population.
Method: UHR patients were invited to complete a battery of measurements at three-time points: at baseline, and at 6 and 12 months of follow-up. Impulsivity was assessed using both behavioral (the Wisconsin Card Sorting Test, WCST) and self-report (the Barratt Impulsiveness Scale, BIS-11) measures.
Results: Findings showed that at 6 months of follow-up, higher 6-month BIS-11 attentional and motor impulsivity were significantly associated with lower quality of life and greater general psychological distress. In addition, higher baseline BIS-11 motor impulsivity significantly predicted more severe positive psychotic symptoms at 12 months of follow-up. However, WCST scores did not show any significant associations with study variables at the different times of follow-up.
Conclusion: Interventions targeting impulsivity in UHR individuals could help decrease psychological distress and positive psychotic symptoms' severity, as well as improve quality of life in UHR individuals.
Competing Interests: Declaration of competing interest None.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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