Increased Prevalence of Binge Eating Disorder and Bulimia Nervosa in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

Autor:	Cooney LG; Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI 54562, USA., Gyorfi K; Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI 54562, USA., Sanneh A; Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI 54562, USA., Bui LM; Department of Obstetrics and Gynecology, Santa Clara Valley Medical Center, Santa Clara, CA 95128, USA., Mousa A; Monash Centre for Health Research and Implementation, Monash University, Melbourne, 3800, Australia., Tay CT; Monash Centre for Health Research and Implementation, Monash University, Melbourne, 3800, Australia.; Endocrine and Diabetes Units, Monash Health, Cayton, 3168, Australia., Teede H; Monash Centre for Health Research and Implementation, Monash University, Melbourne, 3800, Australia.; Endocrine and Diabetes Units, Monash Health, Cayton, 3168, Australia., Stener-Victorin E; Department of Physiology and Pharmacology, Karolinska Institutet, 171 77, Stockholm, Sweden., Brennan L; School of Psychology and Public Health, La Trobe University, Melbourne, 3086, Australia.
Jazyk:	angličtina
Zdroj:	The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2024 Nov 18; Vol. 109 (12), pp. 3293-3305.
DOI:	10.1210/clinem/dgae462
Abstrakt:	Context: Polycystic ovary syndrome (PCOS) is associated with disordered eating/eating disorders, but prior meta-analyses are limited by small numbers. Objective: To inform the 2023 International PCOS Guideline, we performed a systematic review and meta-analysis evaluating the prevalence of disordered eating/eating disorders among women with and without PCOS. Methods: Ovid MEDLINE, EMBASE, PsycInfo, and All EMB were searched from inception through February 1, 2024, for studies that compared prevalences of eating disordered/disordered eating in adolescent or adult women. Random effects meta-analyses were used to estimate the pooled odds ratios (OR) or standardized mean differences (SMD) of outcomes in women with PCOS compared to controls. Methodological quality was assessed by the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system, and included studies were assessed for risk of bias. Results: Of 1352 articles identified, 20 were included, with a total of 28 922 women with PCOS and 258 619 controls. Individuals with PCOS had higher odds of any eating disorder (OR: 1.53 [1.29, 1.82], 8 studies), which persisted in studies where PCOS was diagnosed by Rotterdam criteria (OR: 2.88 [1.55, 5.34], 4 studies). Odds of bulimia nervosa, binge eating disorder, and disordered eating, but not anorexia nervosa, were increased in PCOS. Mean disordered eating scores were higher in PCOS (SMD: 0.52 [0.28, 0.77], 13 studies), including when stratified by normal and higher weight body mass index. Most included studies were of moderate quality, with no evidence of publication bias. Conclusion: Our study informs the 2023 PCOS Guideline recommendations for consideration of the risk of disordered eating/ eating disorders in care of women with PCOS, regardless of weight, especially during providing lifestyle counseling. (© The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. See the journal About page for additional terms.)
Databáze:	MEDLINE
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