What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? A survey and multi-stakeholder debate.
Autor: | Pistollato F; Research and Toxicology, Humane Society International, Brussels, Belgium., Burkhart G; European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), Lisbon, Portugal., Deceuninck P; European Commission, Joint Research Centre (JRC), Ispra, Italy., Bernasconi C; European Commission, Joint Research Centre (JRC), Ispra, Italy., Di Virgilio S; European Commission, Research and Innovation (R&I), Brussels, Belgium., Emili L; InSilicoTrials Technologies, Milan, Italy., Fauvel AC; European Infrastructure for Translational Medicine, Amsterdam, Netherlands., Ferreira Bastos L; Eurogroup for Animals, Brussels, Belgium., Gastaldello A; European Commission, Joint Research Centre (JRC), Ispra, Italy., Gerardi C; Center for Health Regulatory Policies, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy., Habermann JK; BBMRI-ERIC, Biobanking and Biomolecular Resources Research Infrastructure Consortium, Graz, Austria., Hanes I; European Lifestyle Medicine Organization, Geneva, Switzerland., Kyriakopoulou C; European Commission, Research and Innovation (R&I), Brussels, Belgium., Lanka U; Research and Toxicology, Humane Society International, London, United Kingdom., Lauriola P; International Society of Doctors for the Environment, Modena, Italy., Laverty H; Innovative Health Initiative, Brussels, Belgium., Maisonneuve BGC; NETRI - Digitizing Human Biology, Lyon, France., Mennecozzi M; European Commission, Joint Research Centre (JRC), Ispra, Italy., Pappalardo F; Department of Drug and Health Sciences, University of Catania, Catania, Italy., Pastorino R; Section of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy., Radvilaite V; European Innovation Council, Brussels, Belgium., Roggen EL; ToxGenSolutions and 3Rs Management & Consulting ApS, Maastricht, Netherlands., Constantino H; Research and Toxicology, Humane Society International, Brussels, Belgium. |
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Jazyk: | angličtina |
Zdroj: | Frontiers in public health [Front Public Health] 2024 Jul 22; Vol. 12, pp. 1417684. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024). |
DOI: | 10.3389/fpubh.2024.1417684 |
Abstrakt: | In the past decade, significant European calls for research proposals have supported translational collaborative research on non-communicable and infectious diseases within the biomedical life sciences by bringing together interdisciplinary and multinational consortia. This research has advanced our understanding of disease pathophysiology, marking considerable scientific progress. Yet, it is crucial to retrospectively evaluate these efforts' societal impact. Research proposals should be thoughtfully designed to ensure that the research findings can be effectively translated into actionable policies. In addition, the choice of scientific methods plays a pivotal role in shaping the societal impact of research discoveries. Understanding the factors responsible for current unmet public health issues and medical needs is crucial for crafting innovative strategies for research policy interventions. A multistakeholder survey and a roundtable helped identify potential needs for consideration in the EU research and policy agenda. Based on survey findings, mental health disorders, metabolic syndrome, cancer, antimicrobial resistance, environmental pollution, and cardiovascular diseases were considered the public health challenges deserving prioritisation. In addition, early diagnosis, primary prevention, the impact of environmental pollution on disease onset and personalised medicine approaches were the most selected unmet medical needs. Survey findings enabled the formulation of some research-policies interventions (RPIs), which were further discussed during a multistakeholder online roundtable. The discussion underscored recent EU-level activities aligned with the survey-derived RPIs and facilitated an exchange of perspectives on public health and biomedical research topics ripe for interdisciplinary collaboration and warranting attention within the EU's research and policy agenda. Actionable recommendations aimed at facilitating the translation of knowledge into transformative, science-based policies are also provided. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Pistollato, Burkhart, Deceuninck, Bernasconi, Di Virgilio, Emili, Fauvel, Ferreira Bastos, Gastaldello, Gerardi, Habermann, Hanes, Kyriakopoulou, Lanka, Lauriola, Laverty, Maisonneuve, Mennecozzi, Pappalardo, Pastorino, Radvilaite, Roggen and Constantino.) |
Databáze: | MEDLINE |
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