Topical anti-glaucoma medications effects on meibomian glands: Systematic review and meta-analysis.

Autor: Cascaldi BG; Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Cardoso Filho AP; Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Arruda GV; Department of Medical Images, Hematology and Oncology at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Rocha EM; Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Paula JS; Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address: jspaula@fmrp.usp.br.
Jazyk: angličtina
Zdroj: The ocular surface [Ocul Surf] 2024 Aug 05; Vol. 34, pp. 183-193. Date of Electronic Publication: 2024 Aug 05.
DOI: 10.1016/j.jtos.2024.07.011
Abstrakt: Meibomian gland (MG) dysfunction and glaucoma are very prevalent ocular conditions that significantly impact patients' quality of life. A growing number of clinical and experimental studies have reported an association between the use of topical eye drops to reduce intraocular pressure and the development or exacerbation of MG dysfunction. Studies investigating the impact of glaucoma eyedrops on MG diagnostic parameters have shown variable results, particularly regarding the morphology and function of MG and tear film instability. Herein, we corroborated the findings of greater changes in morphological and functional variables related to MG in patients treated with antiglaucoma eye drops through a systematic review and meta-analysis.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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