Probing the toxic hypochlorous acid in natural waters and biosystem by a coumarin-based fluorescence probe.

Autor: Ma J; College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China; Department of Chemistry, Clemson University, Clemson, SC 29634, United States. Electronic address: junyanma@aynu.edu.cn., Zhao M; College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China., Kong X; College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China., Li H; College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China., Xie H; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China., Yang X; College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China., Zhang Z; College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China; Department of Energy and Resource Engineering, College of Engineering, Peking University, Beijing 100871, China. Electronic address: zzx1982@pku.edu.cn.
Jazyk: angličtina
Zdroj: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Sep 01; Vol. 282, pp. 116836. Date of Electronic Publication: 2024 Aug 03.
DOI: 10.1016/j.ecoenv.2024.116836
Abstrakt: Since the onset of the SARS-CoV-2 pandemic in early 2020, there has been a notable rise in sodium hypochlorite disinfectants. Sodium hypochlorite undergoes hydrolysis to generate hypochlorous acid for virus eradication. This chlorine-based disinfectant is widely utilized for public disinfection due to its effectiveness. Although sodium hypochlorite disinfection is convenient, its excessive and indiscriminate use can harm the water environment and pose a risk to human health. Hypochlorous acid, a reactive oxygen species, plays a crucial role in the troposphere, stratospheric chemistry, and oxidizing capacity. Additionally, hypochlorous acid is vital as a reactive oxygen species in biological systems, and its irregular metabolism and level is associated with several illnesses. Thus, it is crucial to identify hypochlorous acid to comprehend its environmental and biological functions precisely. Here, we constructed a new fluorescent probe, utilizing the twisted intramolecular charge transfer mechanism to quickly and accurately detect hypochlorous acid in environmental water and biosystems. The probe showed a notable increase in fluorescence when exposed to hypochlorous acid, demonstrating its excellent selectivity, fast response time (less than 10 seconds), a large Stokes shift (∼ 102 nm), and a low detection limit of 15.5 nM.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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