Congenital and acquired hypothyroidism: Temporal and spatial trends in France from 2014 to 2019.

Autor: Chamot S; Regional Center for Occupational and Environmental Diseases of Hauts-de-France, Amiens University Hospital, 1 rond point du Pr Christian Cabrol, 80000 Amiens, France; Péritox (UMR_I 01), UPJV/INERIS, University of Picardy Jules Verne, 1 rond point du Pr Christian Cabrol, 80000 Amiens, France. Electronic address: chamot.sylvain@chu-amiens.fr., Al-Salameh A; Péritox (UMR_I 01), UPJV/INERIS, University of Picardy Jules Verne, 1 rond point du Pr Christian Cabrol, 80000 Amiens, France; Department of Endocrinology, Diabetes Mellitus and Nutrition, Amiens University Hospital, 1 rond point du Pr Christian Cabrol, 80054 Amiens, France., Balcaen T; CHU Amiens, Medical Information Department, F-80000 Amiens, France; Regional Observatory of Health and Social Issues, Amiens, France., Petit P; Univ. Grenoble Alpes, AGEIS, 38000 Grenoble, France., Bonneterre V; CHU Grenoble Alpes, Centre Régional de Pathologies Professionnelles et Environnementales, 38000 Grenoble, France; Univ. Grenoble Alpes, CNRS, Grenoble INP, TIMC, 38000 Grenoble, France., Cancé C; Univ. Grenoble Alpes, CNRS, Grenoble INP, TIMC, 38000 Grenoble, France., Desailloud R; Péritox (UMR_I 01), UPJV/INERIS, University of Picardy Jules Verne, 1 rond point du Pr Christian Cabrol, 80000 Amiens, France; Department of Endocrinology, Diabetes Mellitus and Nutrition, Amiens University Hospital, 1 rond point du Pr Christian Cabrol, 80054 Amiens, France.
Jazyk: angličtina
Zdroj: Annals of epidemiology [Ann Epidemiol] 2024 Oct; Vol. 98, pp. 18-24. Date of Electronic Publication: 2024 Jul 31.
DOI: 10.1016/j.annepidem.2024.07.091
Abstrakt: Purpose: To assess the incidence of congenital hypothyroidism (CH) and acquired hypothyroidism (AH) between 2014 and 2019 in continental France.
Methods: New cases of CH and AH were identified using the French National Health Data System (Système Nationale des Données de Santé, SNDS). Temporal trends were studied using linear regression models. Spatial distributions were studied using Moran's global index (I) and the statistical method and local indicators of spatial association.
Results: The incidence of permanent CH in females increased by 8.9 % per year (2014: 36.9 [31.1-43.7] per 100,000 birth-years vs. 2019: 51 [43.9-59.3] per 100,000 birth-years, p < 0.01). The incidence of AH decreased between 2014 and 2019 for both females (2014: 535.7 [533.2-538.2] per 100,000 person-years vs 2019: 335.5 [333.6-337.4] per 100,000 person-years, p < 0.01) and males (2014: 197.5 [195.9-199] per 100,000 person-years vs 2019: 141.7 [140.4-142.9] per 100,000 person-years, p < 0.01). The incidence of hypothyroidism was high in the Nord-Pas-De-Calais and Lorraine regions (CH and AH).
Conclusions: The incidence of permanent CH in females has increased over time. AH incidence decreased. It seems necessary to investigate environmental factors in the disparity of incidence distribution.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: