Stereotactic body radiotherapy for spinal oligometastases: a survey on patterns of practice on behalf of the Italian Association of Clinical Oncology and Radiotherapy (AIRO).

Autor: Cuccia F; Radiotherapy Unit, ARNAS Civico Hospital, Palermo, 90145, Italy. francesco.cuccia@arnascivico.it., Franzese C; Radiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy., Badellino S; Department of Oncology, University of Turin, Turin, Italy., Borghetti P; Radiation Oncology Department, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy., Federico M; Radiation Therapy Unit, Clinica Macchiarella, Palermo, Italy., Marvaso G; Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy., Montesi G; Radiation Oncology Unit, Santa Maria della Misericordia Hospital, Rovigo, Italy., Pontoriero A; Radiation Oncology Unit, Department of Biomedical, Dental and Morphological and Functional Imaging Sciences, University of Messina, Messina, Italy., Ferrera G; Radiotherapy Unit, ARNAS Civico Hospital, Palermo, 90145, Italy., Alongi F; Advanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella (VR), Italy.; University of Brescia, Brescia, Italy., Scorsetti M; Radiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, ARNAS Civico Hospital, Milan, Italy.
Jazyk: angličtina
Zdroj: Clinical & experimental metastasis [Clin Exp Metastasis] 2024 Oct; Vol. 41 (5), pp. 679-685. Date of Electronic Publication: 2024 Aug 01.
DOI: 10.1007/s10585-024-10304-3
Abstrakt: Background: The Study Group for the Biology and Treatment of the OligoMetastatic Disease on behalf of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) has conducted a national survey with the aim to depict the current patterns of practice of stereotactic body radiotherapy (SBRT) for spinal oligometastases.
Methods: The Surveymonkey platform was used to send a 28-items questionnaire focused on demographic, clinical and technical aspects related to SBRT for spinal oligometastases. All the AIRO members were invited to fill the questionnaire. Data were then centralized to a single center for analysis and interpretation.
Results: 53 radiation oncologists from 47 centers fulfilled the survey. A complete agreement was observed in proposing SBRT for spinal oligometastases, with the majority considering up to 3 concurrent spine oligometastases feasible for SBRT (73.5%), regardless of spine site (70%), vertebral segment (85%) and morphological features of the lesion (71.7%). Regarding dose prescription, fractionated regimens resulted as the preferred option, either in 3 (58.4%) or five sessions (34%), with a substantial agreement in applying a PTV-margin larger than 1 mm (almost 90% of participants), and ideally using both MRI and PET imaging to improve target volume and organs-at-risk delineation (67.9%).
Conclusions: This national italian survey illustrates the patterns of practice and the main issues for the indication of SBRT for spinal oligometastases. A substantial agreement in the numerical cut-off and vertebral segment involved for SBRT indication was reported, with a slight heterogeneity in terms of dose prescription and fractionation schemes.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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