Median age of patients undergoing total ankle replacement has not significantly changed between 1999 and 2023: A systematic review of prospective studies.

Autor: Bernasconi A; Department of Public Health, Trauma and Orthopaedics, University of Naples Federico II, Naples, Italy. Electronic address: alebernas@gmail.com., Izzo A; Department of Public Health, Trauma and Orthopaedics, University of Naples Federico II, Naples, Italy. Electronic address: izzoantonio1992@gmail.com., Sgadari A; Department of Public Health, Trauma and Orthopaedics, University of Naples Federico II, Naples, Italy. Electronic address: arianna.sgadari@gmail.com., D'Agostino M; Department of Public Health, Trauma and Orthopaedics, University of Naples Federico II, Naples, Italy. Electronic address: martidag93@gmail.com., Mariconda M; Department of Public Health, Trauma and Orthopaedics, University of Naples Federico II, Naples, Italy. Electronic address: maricond@unina.it., Goldberg AJ; The Wellington Hospital, London, United Kingdom. Electronic address: andy@medicalfutures.co.uk.
Jazyk: angličtina
Zdroj: Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons [Foot Ankle Surg] 2024 Jul 19. Date of Electronic Publication: 2024 Jul 19.
DOI: 10.1016/j.fas.2024.07.007
Abstrakt: Introduction: Total ankle replacement (TAR) is an effective treatment for end-stage osteoarthritis. The aim of this systematic review was to assess the age of patients undergoing TAR in prospective comparative studies. Our hypothesis is that the age reported in most recent papers might be lower than those reported in older papers.
Methods: This systematic review was performed using Pubmed, Scopus, EMBASE and Cochrane databases. Only Level I and II studies dealing with TAR were included. Data regarding demographics, study design, number of cohorts in each study, year of publication and year/years in which surgery was performed were extracted. A two-fold analysis was conducted building groups of patients based on the year of publication and creating 1) two groups (before and after the median year) and 2) three groups (using tertiles) in order to compare age of patients operated in different period of times. A comparison was also performed considering the median year of surgery for patients undergoing TAR.
Results: Overall 59 cohorts (42 studies, published between 1999 and 2023; median year of publication: 2017) were included (6397 ankles, 6317 patients, median age 63 years). The difference between the median age for 27 cohorts published until 2016 (weighted median 63 years; IQR, 62.5-64) and the median age for 32 cohorts published after 2017 (weighted median 63.2 years; IQR, 63-67.8) was not statistically significant (p = 0.09). The division in tertiles did not reveal any significant change in the weighted median age at surgery (T1 (1999-2014; 63.2 years; IQR, 62.8-64.1), T2 (2015-2018; 63 years; IQR,63-63.5) and T3 (2019-2023; 63.2 years; IQR, 62.6-67.8)) over time (p = 0.65). The median age of patients operated between 1999 and 2008 vs 2009 and 2023 (data from 48 cohorts) was not different either (p = 0.12).
Conclusion: According to this review of prospective studies published between 1999 and 2023, the median age for patients undergoing TAR over the last two decades has been 63 years, remaining steady with no significant changes over time.
Level of Evidence: Level II - systematic review including Level I and Level II studies.
Competing Interests: Declaration of Competing Interest AB and AJG declare conflicts of interest as reported in the attached ICJME forms. - AB has received support for attending meetings and declares stock options for CURVEBEAM AI. He is in the Board of the International Weightbearing CT Society and Chair of the Youth Committee of the European Foot and Ankle Society. - AJG has received a grant from NIHR HTA for TARVA, consulting fees from Styker Inc and Paragon28, payment or honoraria for lectures from Stryker Inc, Paragon28 and Newclip. He is part of one or more boards in the American Orthopaedic Foot and Ankle Society, British Orthopaedic Foot and Ankle Society and National Joint Registry for England. He declares stock options with the Standing CT Company, Elstree Waterfront Outpatients and SOTA Orthopaedics. AI, AS, MDS and MM declare no conflict of interest directly or indirectly related to this work.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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