Endocrinology During Pregnancy.
| Autor: | Ramírez SI; Department of Family and Community Medicine, Penn State College of Medicine, 500 University Drive, HP11, Hershey, PA 17033, USA. Electronic address: sramirez2@pennstatehealth.psu.edu., Suniega EA; Department of Family Medicine, Tidelands Health Medical University of South Carolina Residency Program, 4320 Holmestown Road, Myrtle Beach, SC 29588, USA., Laughrey MI; Department of Family Medicine, Tidelands Health Medical University of South Carolina Residency Program, 4320 Holmestown Road, Myrtle Beach, SC 29588, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Primary care [Prim Care] 2024 Sep; Vol. 51 (3), pp. 535-547. Date of Electronic Publication: 2024 May 28. |
| DOI: | 10.1016/j.pop.2024.04.009 |
| Abstrakt: | Disequilibrium of hormonal intercommunication between the maternal brain and the developing fetal-placental unit increases morbidity and mortality risk for the mother-baby dyad. As a novel yet temporary endocrine organ, the placenta serves as a physical and immunologic barrier that facilitates exchange of nutrients and elimination of fetal waste. Steroid and peptide-based hormones secreted by the placenta and other neuroendocrine organs induce adaptations in maternal physiology accommodating fetal growth and development and enabling lactation postpartum. Human placental growth hormone, a peptide hormone continuously secreted at increasing concentrations throughout pregnancy, is a primary determinant of maternal insulin resistance and gestational diabetes. Competing Interests: Disclosure The authors have no relevant disclosures. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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