High-Resolution Geospatial Mapping of Zero-Dose and Underimmunized Children Following Nigeria's 2021 Multiple Indicator Cluster Survey/National Immunization Coverage Survey.

Autor:	Jean Baptiste AE; Country Office, World Health Organization, Abuja, Nigeria., Wagai J; Country Office, World Health Organization, Abuja, Nigeria., Hahné S; National Institute for Public Health and the Environment, Bilthoven, the Netherlands., Adeniran A; National Bureau of Statistics, Abuja, Nigeria., Koko RI; Country Office, World Health Organization, Abuja, Nigeria., de Vos S; Groningen Research Institute of Pharmacy, University of Groningen, the Netherlands., Shibeshi M; African Regional Office, World Health Organization, Brazzaville, Congo., Sanders EAM; Department of Paediatric Immunology and Infectious Diseases, University Medical Centre Utrecht, the Netherlands., Masresha B; African Regional Office, World Health Organization, Brazzaville, Congo., Hak E; Groningen Research Institute of Pharmacy, University of Groningen, the Netherlands.
Jazyk:	angličtina
Zdroj:	The Journal of infectious diseases [J Infect Dis] 2024 Jul 25; Vol. 230 (1), pp. e131-e138.
DOI:	10.1093/infdis/jiad476
Abstrakt:	Background: "Zero-dose" children are those who are without any routine vaccination or are lacking the first dose of the diphtheria, tetanus, and pertussis-containing vaccine. Based on global estimates from the World Health Organization/United Nations Children's Fund in 2022, Nigeria has the highest number of zero-dose children, with >2.3 million unvaccinated. Methods: We used data from the 2021 Nigeria Multiple Indicator Cluster Survey/National Immunization Coverage Survey to identify zero-dose and underimmunized children. Geospatial modeling techniques were employed to determine the prevalence of zero-dose children and predict risk areas with underimmunized children at a high resolution (1 × 1 km). Results: Zero-dose and underimmunized children are more prevalent in socially deprived groups. Univariate and multivariate bayesian analyses showed positive correlations between the prevalence of zero-dose and underimmunized children and factors such as stunting, contraceptive prevalence, and literacy. The prevalence of zero-dose and underimmunized children varies significantly by region and ethnicity, with higher rates observed in the country's northern parts. Significant heterogeneity in the distribution of undervaccinated children was observed. Conclusions: Nigeria needs to enhance its immunization system and coverage. Geospatial modeling can help deliver vaccines effectively to underserved communities. By adopting this approach, countries can ensure equitable vaccine access and contribute to global vaccination objectives. Competing Interests: Potential conflicts of interest . All authors: No reported conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. (© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)
Databáze:	MEDLINE
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