Cognitive reserve and executive functions in dual task gait performance in Parkinson's disease.

Autor: Fernández-Lago H; Department of Nursing and Physiotherapy, University of Lleida, Lleida, Spain. helena.fernandez@udl.cat.; Health Care Research Group (GRECS), Lleida Institute for Biomedical Research Dr. Pifarré Foundation, IRBLleida, Lleida, Spain. helena.fernandez@udl.cat.; Grup d'Estudis Societat, Salut, Educació i Cultura, GESEC, Department of Nursing and Physiotherapy, University of Lleida, Carrer de Montserrat Roig, 2, Lleida, 25198, Spain. helena.fernandez@udl.cat., Bosch-Barceló P; Department of Nursing and Physiotherapy, University of Lleida, Lleida, Spain.; Grup d'Estudis Societat, Salut, Educació i Cultura, GESEC, Department of Nursing and Physiotherapy, University of Lleida, Carrer de Montserrat Roig, 2, Lleida, 25198, Spain., Sánchez-Molina JA; Department of Physical Education and Sport, Faculty of Sport Sciences and Physical Education, University of A Coruña, A Coruña, Spain., Ambrus M; Research Center for Sports Physiology, Hungarian University of Sports Science, Budapest, Hungary., Rio D; Department of Physical Education and Sport, Faculty of Sport Sciences and Physical Education, University of A Coruña, A Coruña, Spain., Fernández-Del-Olmo MÁ; Sports Science Research Center, King Juan Carlos University, Madrid, Spain.
Jazyk: angličtina
Zdroj: Experimental brain research [Exp Brain Res] 2024 Sep; Vol. 242 (9), pp. 2271-2278. Date of Electronic Publication: 2024 Jul 25.
DOI: 10.1007/s00221-024-06897-6
Abstrakt: A higher level of education was correlated with less severe motor impairment in Parkinson's Disease (PD). Nevertheless, there is limited evidence on the relationship between cognitive reserve and motor performance in complex situations in PD. To investigate the association between cognitive reserve and the dual-task gait effect in PD. Additionally, we examined the relationship between executive function, clinical and sociodemographic variables and, dual-task gait effects. We conducted a cross-sectional study with 44 PD participants. We evaluated dual-task effect on cadence, stride length, and gait velocity. Dual-task effects were correlated with neurophysiological factors, including cognitive reserve (Cognitive Reserve Index Questionnaire), overall cognitive performance of executive functions, a specific executive function domain (Trail Making Test), and the global cognitive status (Montreal Cognitive Assessment and Mini-Mental State Examination). Age, gender, and disease severity were considered as variables to be examined for correlation. We found that cognitive reserve did not influence gait performance under dual-task conditions in this sample. However, executive functions, age, and disease severity were associated with the dual-task effect on gait. The overall cognitive performance with respect to the Trail Making Test showed an inverse relationship in the dual-task gait effect on cadence. Our study's findings have important implications for understanding the association between executive functions, age, and disease severity with the dual-task effect on gait in PD. Pre-life factors, such as education, occupation, and leisure activity, did not contribute to coping with complex gait situations in PD.
(© 2024. The Author(s).)
Databáze: MEDLINE
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