Nuclear medicine imaging modalities to detect incidentalomas and their impact on patient management: a systematic review.

Autor: Costanzo R; Department of Biomedicine Neurosciences and Advanced Diagnostics, Neurosurgical Clinic, AOUP 'Paolo Giaccone', School of Medicine, University of Palermo, Palermo, Italy., Scalia G; Neurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy. gianluca.scalia@outlook.it., Strigari L; Department of Medical Physics, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Ippolito M; Department of Advanced Technologies, Nuclear Medicine and PET, Cannizzaro Hospital, Catania, Italy., Paolini F; Department of Biomedicine Neurosciences and Advanced Diagnostics, Neurosurgical Clinic, AOUP 'Paolo Giaccone', School of Medicine, University of Palermo, Palermo, Italy., Brunasso L; Department of Biomedicine Neurosciences and Advanced Diagnostics, Neurosurgical Clinic, AOUP 'Paolo Giaccone', School of Medicine, University of Palermo, Palermo, Italy., Sciortino A; Department of Biomedicine Neurosciences and Advanced Diagnostics, Neurosurgical Clinic, AOUP 'Paolo Giaccone', School of Medicine, University of Palermo, Palermo, Italy., Iacopino DG; Department of Biomedicine Neurosciences and Advanced Diagnostics, Neurosurgical Clinic, AOUP 'Paolo Giaccone', School of Medicine, University of Palermo, Palermo, Italy., Maugeri R; Department of Biomedicine Neurosciences and Advanced Diagnostics, Neurosurgical Clinic, AOUP 'Paolo Giaccone', School of Medicine, University of Palermo, Palermo, Italy., Ferini G; Radiation Oncology Unit, REM Radioterapia Srl, Viagrande, Italy., Viola A; Radiation Oncology Unit, REM Radioterapia Srl, Viagrande, Italy., Zagardo V; Radiation Oncology Unit, REM Radioterapia Srl, Viagrande, Italy., Cosentino S; Department of Advanced Technologies, Nuclear Medicine and PET, Cannizzaro Hospital, Catania, Italy., Umana GE; Department of Neurosurgery, Trauma and Gamma-Knife Center, Cannizzaro Hospital, Catania, Italy.; Department of Medicine and Surgery, Kore University of Enna, Enna, Italy.
Jazyk: angličtina
Zdroj: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2024 Jul 25; Vol. 150 (7), pp. 368. Date of Electronic Publication: 2024 Jul 25.
DOI: 10.1007/s00432-024-05891-3
Abstrakt: Purpose: This systematic review aims to investigate the role of nuclear imaging techniques in detecting incidentalomas and their impact on patient management.
Methods: Following PRISMA guidelines, a comprehensive literature search was conducted from February to May 2022. Studies in English involving patients undergoing nuclear medicine studies with incidental tumor findings were included. Data on imaging modalities, incidentaloma characteristics, management changes, and follow-up were extracted and analyzed.
Results: Ninety-two studies involving 64.884 patients were included. Incidentalomas were detected in 611 cases (0.9%), with thyroid being the most common site. PET/CT with FDG and choline tracers showed the highest incidentaloma detection rates. Detection of incidentalomas led to a change in therapeutic strategy in 59% of cases. Various radiotracers demonstrated high sensitivity for incidentaloma detection, particularly in neuroendocrine tumors and prostate cancer.
Conclusion: Nuclear imaging techniques play a crucial role in detecting incidentalomas, leading to significant changes in patient management. The high sensitivity of these modalities highlights their potential in routine oncology follow-up protocols. Future directions may include enhancing spatial resolution and promoting theranostic approaches for improved patient care.
(© 2024. The Author(s).)
Databáze: MEDLINE
Externí odkaz: