Histone (de)acetylation in epigenetic regulation of Phytophthora pathobiology.

Autor: Guan Y; Department of Plant Ecophysiology, Institute of Experimental Biology, Faculty of Biology, Adam Mickiewicz University in Poznań, Poznań, Poland., Gajewska J; Department of Plant Ecophysiology, Institute of Experimental Biology, Faculty of Biology, Adam Mickiewicz University in Poznań, Poznań, Poland., Floryszak-Wieczorek J; Department of Plant Physiology, Poznań University of Life Sciences, Poznań, Poland., Tanwar UK; Department of Plant Physiology, Faculty of Biology, Adam Mickiewicz University in Poznań, Poznań, Poland., Sobieszczuk-Nowicka E; Department of Plant Physiology, Faculty of Biology, Adam Mickiewicz University in Poznań, Poznań, Poland., Arasimowicz-Jelonek M; Department of Plant Ecophysiology, Institute of Experimental Biology, Faculty of Biology, Adam Mickiewicz University in Poznań, Poznań, Poland.
Jazyk: angličtina
Zdroj: Molecular plant pathology [Mol Plant Pathol] 2024 Jul; Vol. 25 (7), pp. e13497.
DOI: 10.1111/mpp.13497
Abstrakt: Phytophthora species are oomycetes that have evolved a broad spectrum of biological processes and improved strategies to cope with host and environmental challenges. A growing body of evidence indicates that the high pathogen plasticity is based on epigenetic regulation of gene expression linked to Phytophthora's rapid adjustment to endogenous cues and various stresses. As 5mC DNA methylation has not yet been identified in Phytophthora, the reversible processes of acetylation/deacetylation of histone proteins seem to play a pivotal role in the epigenetic control of gene expression in oomycetes. To explore this issue, we review the structure, diversity, and phylogeny of histone acetyltransferases (HATs) and histone deacetylases (HDACs) in six plant-damaging Phytophthora species: P. capsici, P. cinnamomi, P. infestans, P. parasitica, P. ramorum, and P. sojae. To further integrate and improve our understanding of the phylogenetic classification, evolutionary relationship, and functional characteristics, we supplement this review with a comprehensive view of HATs and HDACs using recent genome- and proteome-level databases. Finally, the potential functional role of transcriptional reprogramming mediated by epigenetic changes during Phytophthora species saprophytic and parasitic phases under nitro-oxidative stress is also briefly discussed.
(© 2024 The Author(s). Molecular Plant Pathology published by British Society for Plant Pathology and John Wiley & Sons Ltd.)
Databáze: MEDLINE
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