Parental Assessment of Infantile Hemangioma Cosmetic Clinical Outcomes: Results of the Spanish Hemangioma Nationwide Prospective Cohort.

Autor:	Colmenero-Sendra M; Dermatology Department, Hospital Costa del Sol, Marbella, Spain; Programa de Doctorado en Medicina Clínica y Salud Pública, Universidad de Granada, Spain., Del Boz-González J; Dermatology Department, Hospital Regional Universitario de Málaga, Spain. Electronic address: javierdelboz@yahoo.es., Baselga Torres E; Dermatology Department, Hospital Sant Joan de Déu, Universitat Autònoma de Barcelona, Spain., Bernabéu-Wittel J; Dermatology Department, Hospital Virgen del Rocío, Sevilla, Spain; Dermatology Department, Hospital Viamed Santa Ángela de la Cruz, Sevilla, Spain., Roé-Crespo E; Dermatology Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain., Vicente A; Dermatology Department, Hospital Sant Joan de Déu, Barcelona, Spain., Valdivieso-Ramos M; Dermatology Department, Hospital Infanta Leonor, Madrid, Spain., Martín-Santiago A; Dermatology Department, Hospital Son Espases, Palma de Mallorca, Spain., Palencia-Pérez SI; Dermatology Department, Hospital 12 de Octubre, Madrid, Spain., Montserrat-García MT; Dermatology Department, Hospital Virgen del Rocío, Sevilla, Spain; Dermatology Department, Hospital Viamed Santa Ángela de la Cruz, Sevilla, Spain., Azón-Masoliver A; Dermatology Department, Hospital Sant Joan de Reus, Tarragona, Spain., Dañino M; Dermatology Department, Hospital Virgen del Rocío, Sevilla, Spain., Tubau Prims C; Dermatology Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain., Prat C; Dermatology Department, Hospital Sant Joan de Déu, Barcelona, Spain., Giacaman A; Dermatology Department, Hospital Son Espases, Palma de Mallorca, Spain., Domínguez-Cruz JJ; Dermatology Department, Hospital Virgen del Rocío, Sevilla, Spain; Dermatology Department, Hospital Viamed Santa Ángela de la Cruz, Sevilla, Spain., Bauzá Alonso A; Dermatology Department, Hospital Son Espases, Palma de Mallorca, Spain., Grau-Pérez M; Research Unit, Fundación Piel Sana AEDV, Madrid, Spain; Dermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Descalzo MÁ; Research Unit, Fundación Piel Sana AEDV, Madrid, Spain., García-Doval I; Research Unit, Fundación Piel Sana AEDV, Madrid, Spain; Dermatology Department, Complejo Hospitalario Universitario de Vigo, Vigo, Spain.
Jazyk:	English; Spanish; Castilian
Zdroj:	Actas dermo-sifiliograficas [Actas Dermosifiliogr] 2024 Jul 18. Date of Electronic Publication: 2024 Jul 18.
DOI:	10.1016/j.ad.2024.06.010
Abstrakt:	Background: Functional impairment is the main consideration when it comes to choosing therapy for infantile hemangiomas (IH). However, since most hemangiomas are treated for cosmetic reasons, it is important to know the cosmetic outcome assessed by the parents. Objective: To evaluate the aesthetic outcomes of IH, considering the characteristics of the lesions and the treatments used. Patients and Methods: The Spanish Infantile Hemangioma Nationwide Prospective Cohort (2016-2022) recruited all consecutive patients diagnosed with IH in 12 Spanish hospitals. The children included had two photos of the IH lesion (at both baseline and at the end of the study). A panel of parents blindly assessed all available photos using a scale from 0 (worst cosmetic outcomes) to 10 (best cosmetic outcomes). The different scores - both before and after treatment - as well as the outcomes percent considered excellent (>9) were described and compared. We analyzed the effect of receiving different therapies and performed causal model analyses estimating the mean treatment effect of parents' assessments. Results: The median follow-up was 3.1 years. A total of 824 photos were evaluated. Baseline aesthetic impact was higher in the propranolol group vs the topical timolol and observation treatment groups (1.85 vs 3.14 vs 3.66 respectively; p<0.001). After treatment, the aesthetic impact was similar between both treatment groups (7.59 vs 7.93 vs 7.90; p>0.2). The causal model could only be applied to the comparison between topical timolol and observation, revealing no differences whatsoever. Conclusion: This is the first prospective cohort to analyze the aesthetic outcome of IH. The final aesthetic results of the three therapies were similar, with nearly 40% of patients achieving excellent aesthetic outcomes. (Copyright © 2024 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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