Technological modes and processes to enhance the Rhodosporidium toruloides based lipid accumulation.

Autor: Wankhede L; Department of Civil Engineering, Lassonde School of Engineering, York University, North York, Toronto, Ontario M3J 1P3, Canada., Bhardwaj G; Department of Civil Engineering, Lassonde School of Engineering, York University, North York, Toronto, Ontario M3J 1P3, Canada., Saini R; Department of Civil Engineering, Lassonde School of Engineering, York University, North York, Toronto, Ontario M3J 1P3, Canada., Osorio-Gonzalez CS; Department of Civil Engineering, Lassonde School of Engineering, York University, North York, Toronto, Ontario M3J 1P3, Canada., Brar SK; Department of Civil Engineering, Lassonde School of Engineering, York University, North York, Toronto, Ontario M3J 1P3, Canada. Electronic address: satinder.brar@lassonde.yorku.ca.
Jazyk: angličtina
Zdroj: Microbiological research [Microbiol Res] 2024 Oct; Vol. 287, pp. 127840. Date of Electronic Publication: 2024 Jul 16.
DOI: 10.1016/j.micres.2024.127840
Abstrakt: Rhodosporidium toruloides has emerged as an excellent option for microbial lipid production due to its ability to accumulate up to 70 % of lipids per cell dry weight, consume multiple substrates such as glucose and xylose, and tolerate toxic compounds. Despite the potential of Rhodosporidium toruloides for high lipid yields, achieving these remains is a significant hurdle. A comprehensive review is essential to thoroughly evaluate the advancements in processes and technologies to enhance lipid production in R. toruloides. The review covers various strategies for enhancing lipid production like co-culture, adaptive evolution, carbon flux analysis, as well as different modes of fermentation. This review will help researchers to better understand the recent developments in technologies for sustainable and scalable lipid production from R. toruloides and simultaneously emphasize the need for developing an efficient and sustainable bioprocess.
Competing Interests: Declarations of Competing Interest The authors have no relevant financial or non-financial interests to disclose.
(Copyright © 2024 The Authors. Published by Elsevier GmbH.. All rights reserved.)
Databáze: MEDLINE
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