Clinical Characteristics of Hospitalized Patients With COVID-19 and Their Association With the Progression to Critical Illness and Death: A Single-Center Retrospective Study From Northwestern Mexico.

Autor: Martínez-Villa FA; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Departamento de Medicina general, Unidad de Medicina Familiar No. 21, IMSS, La Cruz de Elota, Sinaloa, Mexico., Angulo-Zamudio UA; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico., Leon-Sicairos N; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Research Department, Pediatric Hospital of Sinaloa, Culiacan, Sinaloa, Mexico., González-Esparza R; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Departamento de Medicina general, Unidad de Medicina Familiar No. 21, IMSS, La Cruz de Elota, Sinaloa, Mexico., Sanchez-Cuen J; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Research Department, Hospital Regional, ISSSTE, Culiacán, Sinaloa, Mexico., Martinez-Garcia JJ; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Research Department, Pediatric Hospital of Sinaloa, Culiacan, Sinaloa, Mexico., Flores-Villaseñor H; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Molecular Biology Department, The Sinaloa State Public Health Laboratory, Secretariat of Health, Culiacan, Sinaloa, Mexico., Medina-Serrano J; Research Department, Coordinación de Investigación en Salud, Delegacion IMSS, Culiacan, Sinaloa, Mexico., Canizalez-Roman A; School of Medicine, Autonomous University of Sinaloa, Culiacan, Sinaloa, Mexico.; Research Department, The Women's Hospital, Secretariat of Health, Culiacan, Sinaloa, Mexico.
Jazyk: angličtina
Zdroj: The clinical respiratory journal [Clin Respir J] 2024 Jul; Vol. 18 (7), pp. e13813.
DOI: 10.1111/crj.13813
Abstrakt: Objective: The objective of this study was to associate the epidemiological and clinical characteristics of patients hospitalized for COVID-19 with the progression to critical illness and death in northwestern Mexico.
Methods: From March to October 2020, we collected the demographic and clinical characteristics of 464 hospitalized patients from northwestern Mexico.
Results: Sixty-four percent (295/464) of the patients became critically ill. Age, occupation, steroid and antibiotic use at previous hospitalization, and underlying diseases (hypertension, obesity, and chronic kidney disease) were associated with critical illness or death (p: < 0.05). No symptoms were associated with critical illness. However, the parameters such as the heart rate, respiratory rate, oxygen saturation, and diastolic pressure and the laboratory parameters such as the glucose, creatinine, white line cells, hemoglobin, D-dimer, and C-reactive protein, among others, were associated with critical illness (p: < 0.05). Finally, advanced age, previous hospital treatment, and the presence of one or more underlying diseases were associated with critical illness and death (p: < 0.02).
Conclusions: Several epidemiological (e.g., age and occupation) and clinical factors (e.g., previous treatment, underlying diseases, and vital signs and laboratory parameters) were associated with critical illness and death in patients hospitalized with COVID-19. These data provide us with possible markers to avoid critical illness or death from COVID-19 in our region.
(© 2024 The Author(s). The Clinical Respiratory Journal published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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