Differences in self-reported signs related to central sensitization and pressure pain threshold related to knee osteoarthritis and sarcopenia.

Autor: Imai R; Graduate School of Rehabilitation, Osaka Kawasaki Rehabilitation University, 158 Mizuma, Kaizuka City, Osaka, 597-0104, Japan. imair@kawasakigakuen.ac.jp., Tanaka S; Department of Clinical Research Center, Fukuoka Orthopaedic Hospital, 2-10-50 Yanagochi, Minami-ku, Fukuoka, Fukuoka, 815-0063, Japan., Kubo T; Graduate School of Rehabilitation, Osaka Kawasaki Rehabilitation University, 158 Mizuma, Kaizuka City, Osaka, 597-0104, Japan., Hida M; Graduate School of Rehabilitation, Osaka Kawasaki Rehabilitation University, 158 Mizuma, Kaizuka City, Osaka, 597-0104, Japan., Nakao H; Department of Physical Therapy, Faculty of Social Work Studies, Josai International University, Togane City, Chiba, 283-0002, Japan., Imaoka M; Graduate School of Rehabilitation, Osaka Kawasaki Rehabilitation University, 158 Mizuma, Kaizuka City, Osaka, 597-0104, Japan., Nishigami T; Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, 1-1 Gakuen-cho, Mihara, Hiroshima, 723-0053, Japan.
Jazyk: angličtina
Zdroj: European geriatric medicine [Eur Geriatr Med] 2024 Jul 16. Date of Electronic Publication: 2024 Jul 16.
DOI: 10.1007/s41999-024-01018-6
Abstrakt: Purpose: Neuroinflammation, which occurs in knee osteoarthritis and sarcopenia, has attracted attention as a mechanism of central sensitization, but the relationship between central sensitization and these conditions has not been widely studied. This study investigates differences in self-reported signs of central sensitization and pressure pain threshold in individuals with knee osteoarthritis and sarcopenia.
Methods: We examined 340 patients (mean age ± standard deviation: 76 ± 5.9, women were 86.9%) with knee osteoarthritis scheduled to undergo total knee arthroplasty. For comparison, 129 community-dwelling older people (mean age ± standard deviation: 76 ± 5.5, women were 68.9%) individuals without a history of knee osteoarthritis or any other diagnosed illnesses were matched for age and sex. We assessed central sensitization inventory-9, pressure pain threshold, pain-related factors, skeletal muscle mass index, and hand grip strength. ANCOVA using 2 (patients with knee osteoarthritis and community older people without knee osteoarthritis) × 2 (sarcopenia and robust) was performed to assess outcome measurements.
Results: The prevalence of sarcopenia among patients with knee osteoarthritis was 50.3%. ANCOVA revealed an interaction effect for the central sensitization inventory-9. For the main effect of knee osteoarthritis, there was a significant difference in central sensitization inventory-9, and for the main effect of sarcopenia, there was a significant difference in pressure pain threshold.
Conclusions: Discrepancies in the evaluation of central sensitization were identified between knee osteoarthritis and sarcopenia. Individuals with knee osteoarthritis had elevated score of self-reported indications of central sensitization, whereas sarcopenic patients had reduced pressure pain thresholds.
(© 2024. The Author(s), under exclusive licence to European Geriatric Medicine Society.)
Databáze: MEDLINE
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