Extracorporeal membrane oxygenation-facilitated palliative radiotherapy for severe airway obstruction due to lung cancer: A case report.

Autor: Mori H; Department of Emergency and Critical Care Medicine Hachinohe City Hospital Hachinohe Aomori Japan.; Present address: Department of Emergency and Critical Care Medicine Saitama Medical Center, Jichi Medical University Saitama Japan., Kashiura M; Department of Emergency and Critical Care Medicine Saitama Medical Center, Jichi Medical University Saitama Japan., Yoshimura Y; Department of Emergency and Critical Care Medicine Hachinohe City Hospital Hachinohe Aomori Japan., Yamahata Y; Department of Emergency and Critical Care Medicine Hachinohe City Hospital Hachinohe Aomori Japan.; Present address: Transitional & Palliative Care Aso Iizuka Hospital Iizuka Fukuoka Japan., Tokura T; Department of Emergency and Critical Care Medicine Hachinohe City Hospital Hachinohe Aomori Japan., Nodagashira T; Department of Emergency and Critical Care Medicine Hachinohe City Hospital Hachinohe Aomori Japan., Konn A; Department of Emergency and Critical Care Medicine Hachinohe City Hospital Hachinohe Aomori Japan., Moriya T; Department of Emergency and Critical Care Medicine Saitama Medical Center, Jichi Medical University Saitama Japan.
Jazyk: angličtina
Zdroj: Acute medicine & surgery [Acute Med Surg] 2024 Jul 14; Vol. 11 (1), pp. e980. Date of Electronic Publication: 2024 Jul 14 (Print Publication: 2024).
DOI: 10.1002/ams2.980
Abstrakt: Background: The use of venovenous extracorporeal membrane oxygenation (VV-ECMO), particularly during radiotherapy, for severe malignant central airway obstruction has rarely been reported.
Case Presentation: A 47-year-old female presented to our emergency department with severe respiratory distress. Given her medical history, she was initially diagnosed with asthma. Despite initial treatment, which included intubation, her condition deteriorated, necessitating VV-ECMO. Computed tomography performed following the initiation of VV-ECMO revealed extensive lung cancer involving both bronchial types. Radiotherapy while on VV-ECMO led to a significant reduction in tumor size, allowing for the weaning of ECMO support and successful extubation.
Conclusion: Malignant central airway obstruction is life-threatening. Our case demonstrates the efficacy of combining VV-ECMO with radiotherapy when conventional therapies fail. Further research is necessary to validate and explore this novel approach's implications.
Competing Interests: Dr. Takashi Moriya is an Editorial Board member of AMS Journal and a co‐author of this article. To minimize bias, they were excluded from all editorial decision‐making related to the acceptance of this article for publication.
(© 2024 The Author(s). Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine.)
Databáze: MEDLINE
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