SignalP: The Evolution of a Web Server.
| Autor: | Nielsen H; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark. henni@dtu.dk., Teufel F; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.; Digital Science & Innovation, Novo Nordisk A/S, Malov, Denmark., Brunak S; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., von Heijne G; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.; Science for Life Laboratory, Stockholm University, Solna, Sweden. |
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| Jazyk: | angličtina |
| Zdroj: | Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2836, pp. 331-367. |
| DOI: | 10.1007/978-1-0716-4007-4_17 |
| Abstrakt: | SignalP ( https://services.healthtech.dtu.dk/services/SignalP-6.0/ ) is a very popular prediction method for signal peptides, the intrinsic signals that make proteins secretory. The SignalP web server has existed since 1995 and is now in its sixth major version. In this historical account, we (three authors who have taken part in the entire journey plus the first author of the latest version) describe the differences between the versions and discuss the various decisions taken along the way. (© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.) |
| Databáze: | MEDLINE |
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