A Systematic Review of Symptoms of Pernicious Anemia.
| Autor: | Seage CH; Cardiff School of Sport & Health Sciences, Cardiff Metropolitan University, Cardiff, Wales, United Kingdom., Bennett A; Applied Psychology, Cardiff School of Sport & Health Sciences, Cardiff Metropolitan University, Cardiff, Wales, United Kingdom., Ward N; Clinical Pharmacy and Pharmacy Practice, Leicester School of Pharmacy, De Montfort University, Gateway, Leicester, United Kingdom., Semedo L; School of Healthcare Sciences, Cardiff University, Cardiff, Wales, United Kingdom., Plattel CHM; B12 Research Institute Foundation, Rotterdam, the Netherlands., Suijker KIM; B12 Research Institute Foundation, Rotterdam, the Netherlands.; Department of Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Vis JY; Department of Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, the Netherlands., James DH; Health Psychology in Pharmacy Practice, Cardiff School of Sport & Health Sciences, Cardiff Metropolitan University, Cardiff, Wales, United Kingdom. |
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| Jazyk: | angličtina |
| Zdroj: | Food and nutrition bulletin [Food Nutr Bull] 2024 Jun; Vol. 45 (1_suppl), pp. S34-S39. |
| DOI: | 10.1177/03795721241227016 |
| Abstrakt: | Background: Pernicious anemia (PA) is a type of macrocytic anemia caused by autoimmune gastritis. To facilitate timely diagnosis and treatment of PA there is a pressing need for improved understanding among Healthcare providers of the condition's symptoms and diagnostic criteria. Objective: This systematic review aims to extend existing clinical knowledge on the presentation of PA by determining which symptoms and clinical complications are reported in published adult case studies. Methods: Relevant studies were identified through electronic searches of PsycINFO, Embase, and MEDLINE, via OvidSP. During data extraction symptoms were categorized according to the International Classification of Diseases and were grouped based on frequency. Results: Symptoms were documented for 103 adults with a diagnosis of PA; the most frequent symptoms were fatigue (55%), loss of sensation in limbs (32%), excessive weight loss (27%), and a sore tongue (23%). Conclusions: This review highlights the diverse symptomology of adults who are diagnosed with PA. Most symptoms documented in case studies are consistent with the core signs of B Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Databáze: | MEDLINE |
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