Variations in Microwave Ablation Zones as a Function of Probe Spacing, Angulation, and Geometry.

Autor: Huth H; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland. Electronic address: hannah.huth@nih.gov., Negussie AH; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland., Saccenti L; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland., Borde T; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland., Varble NA; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland; Philips Healthcare, Best, the Netherlands., Xu S; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland., Kassin MT; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland., Ukeh IN; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland., Wood BJ; Center for Interventional Oncology, Radiology, and Imaging Sciences, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland; National Cancer Institute and National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland.
Jazyk: angličtina
Zdroj: Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2024 Oct; Vol. 35 (10), pp. 1558-1564. Date of Electronic Publication: 2024 Jul 06.
DOI: 10.1016/j.jvir.2024.06.033
Abstrakt: Despite advancements in precision and effectiveness of microwave ablation for tumor management, accurately predicting ablation zone geometry and minimum ablation margin remains a major challenge. This pilot study aimed to elucidate the influence of probe configuration on the morphometry of resulting ablation zones using tissue-mimicking thermochromic phantoms. In vitro results from 12 ablations were analyzed: (a) a single-probe ablation (n = 1) and (b) dual-probe ablations (n = 11). Angles and separations greatly influenced ablation zone morphometry. In dual-probe ablations, probe tip separation and angle of offset were positively correlated with ablation zone volume, length, and cross-sectional circularity. Interventional radiology ablation planning is currently suboptimal as it often relies on cognitive registration. Even treatment planning software creates virtual composite ablation volumes based on data from theoretical ablations in single, idealized configurations and settings. These findings draw attention to a need for improved ablation zone prediction and planning, which might impact efficiency, safety, cost, and outcomes.
(Published by Elsevier Inc.)
Databáze: MEDLINE