Association between post-COVID-19 conditions and male semen quality in Japan: A descriptive investigation.

Autor: Maruki T; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan., Morioka S; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: shmorioka@hosp.ncgm.go.jp., Miyazato Y; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan; Department of General Internal Medicine, Hashimoto Municipal Hospital, Wakayama, Japan., Tsuzuki S; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan., Takezawa K; Department of Urology, Osaka University Graduate School of Medicine, Japan., Kuribayashi S; Department of Urology, Osaka University Graduate School of Medicine, Japan., Kutsuna S; Department of Infection Control, Osaka University Graduate School of Medicine/Faculty of Medicine, Japan., Ohmagari N; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan., Fukuhara S; Department of Urology, Osaka University Graduate School of Medicine, Japan.
Jazyk: angličtina
Zdroj: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2024 Nov; Vol. 30 (11), pp. 1194-1196. Date of Electronic Publication: 2024 Jun 27.
DOI: 10.1016/j.jiac.2024.06.021
Abstrakt: Some reports suggest that coronavirus disease 2019 (COVID-19) may affect male reproductive function. There is also concern in Japan that COVID-19 may contribute to the pre-existing decline in male fertility; however, no studies have investigated the effects of COVID-19 on male reproductive function. In this study, we aimed to analyze the semen quality of men who had recovered from COVID-19. Male patients who had recovered from COVID-19 between February 2020 and September 2021 were recruited for this study. Participants were sent a semen collection kit; they were asked to collect semen at home and deliver it to a laboratory at Osaka University. We used these samples to analyze sperm concentration, total sperm count, and semen volume. In total, 125 participants were included in this study. The median age of all patients was 46 years (interquartile range (IQR): 38-52 years). The severity of COVID-19 was mild in 80 patients; 19 were moderate I, 22 were moderate II, and four were severe. The median semen volume was 2.5 mL (IQR: 1.8-3.1), the median sperm concentration was 98.9 million/mL (IQR: 43.8-162.2), and the median total sperm count was 212.1 million (IQR: 89.7-368.2). In a previous study in Japan, the median sperm count in adult men was reported to be 201 million. Participants in our study did not have lower sperm counts than this, despite their older age. Our results suggest that the long-term effects of COVID-19 on spermatogenesis are minimal.
Competing Interests: Declarations of competing interest None.
(Copyright © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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