A novel titanium alloy for load-bearing biomedical implants: Evaluating the antibacterial and biocompatibility of Ti536 produced via electron beam powder bed fusion additive manufacturing process.
Autor: | Behjat A; Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran; Integrated Additive Manufacturing Center, Department of Management and Production Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy., Sanaei S; Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran., Mosallanejad MH; Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran; Integrated Additive Manufacturing Center, Department of Management and Production Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy., Atapour M; Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran. Electronic address: M.atapour@cc.iut.ac.ir., Sheikholeslam M; Department of Biomaterials, Tissue Engineering and Nanotechnology, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran., Saboori A; Integrated Additive Manufacturing Center, Department of Management and Production Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. Electronic address: Abdollah.saboori@polito.it., Iuliano L; Integrated Additive Manufacturing Center, Department of Management and Production Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. |
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Jazyk: | angličtina |
Zdroj: | Biomaterials advances [Biomater Adv] 2024 Oct; Vol. 163, pp. 213928. Date of Electronic Publication: 2024 Jun 18. |
DOI: | 10.1016/j.bioadv.2024.213928 |
Abstrakt: | Additive manufacturing (AM) of Ti-based biomedical implants is a pivotal research topic because of its ability to produce implants with complicated geometries. Despite desirable mechanical properties and biocompatibility of Ti alloys, one major drawback is their lack of inherent antibacterial properties, increasing the risk of postoperative infections. Hence, this research focuses on the Ti536 (Ti5Al3V6Cu) alloy, developed through Electron Beam Powder Bed Fusion (EB-PBF), exploring bio-corrosion, antibacterial features, and cell biocompatibility. The microstructural characterization revealed grain refinement and the formation of Ti Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
Databáze: | MEDLINE |
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