A Meta-analysis of the Effect of Probiotic Lactobacillus sp. as Immunomodulating Inflammatory Responses.
| Autor: | Ervina WF; Postgraduate School of Universitas Airlangga, Master of Immunology Program, Surabaya, Indonesia.; National Research and Innovation Agency, Cibinong, Indonesia., Madyawati SP; Post Graduate School of Universitas Airlangga, Surabaya, Indonesia., Saputro ID; Soetomo General Academic Hospital, Surabaya, Indonesia., Safari D; National Research and Innovation Agency, Cibinong, Indonesia., Putri RE; Postgraduate School of Universitas Airlangga, Master of Forensic Program, Surabaya, Indonesia., Zulqaida S; Postgraduate School of Universitas Airlangga, Master of Immunology Program, Surabaya, Indonesia. |
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| Jazyk: | angličtina |
| Zdroj: | Medeniyet medical journal [Medeni Med J] 2024 Jun 28; Vol. 39 (2), pp. 122-131. |
| DOI: | 10.4274/MMJ.galenos.2024.53822 |
| Abstrakt: | Lactobacillus sp. is considered an indispensable probiotic, and this probiotic has an effective role in maintaining the immune system. We evaluated the effect of the probiotic Lactobacillus sp. on modulating inflammation in several cases. In collecting the literature, we used databases from the Web of Science, the Cochrane Central Register of Controlled Trials, PubMed, and Embase. Studies that met the inclusion criteria were analyzed using Review Manager (version 5.4). A p-value of <0.05 of the total effect is considered statistically significant. Finally, 1895 references were retrieved and 20 were included in the meta-analysis. This meta-analysis suggested that most cases in this study were healthy elderly who received treatment with Lactobacillus sp. Lactobacillus sp. has a positive effect on B cells, eosinophils, IgE, NK cells, TNF-α, and IL-10. Lactobacillus could regulate the immune system by modulating inflammation in the healthy elderly. Competing Interests: Conflict of Interest: The authors have no conflict of interest to declare. (Copyright© 2024 The Author. Published by Galenos Publishing House on behalf of Istanbul Medeniyet University Faculty of Medicine.) |
| Databáze: | MEDLINE |
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