Messaging About HIV Transmission Risk When Viral Load Is Undetectable: Reactions and Perceived Accuracy Among US Sexual Minority Men.

Autor: Calabrese SK; Department of Psychological and Brain Sciences, George Washington University, Washington, DC.; Department of Prevention and Community Health, George Washington University, Washington, DC., Zaheer MA; Department of Psychological and Brain Sciences, George Washington University, Washington, DC.; School of Medicine and Health Sciences, George Washington University, Washington, DC., Flores JJ; Department of Psychological and Brain Sciences, George Washington University, Washington, DC., Kalwicz DA; Department of Psychological and Brain Sciences, George Washington University, Washington, DC., Modrakovic X; Department of Psychological and Brain Sciences, George Washington University, Washington, DC., Rao S; Department of Psychological and Brain Sciences, George Washington University, Washington, DC., Dovidio JF; Department of Psychology, Yale University, New Haven, CT; and., Zea MC; Department of Psychological and Brain Sciences, George Washington University, Washington, DC., Eaton LA; Department of Human Development and Family Sciences, University of Connecticut, Storrs, CT.
Jazyk: angličtina
Zdroj: Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2024 Jul 01; Vol. 96 (3), pp. 270-279.
DOI: 10.1097/QAI.0000000000003417
Abstrakt: Background: Scientific evidence indicates that HIV viral suppression to an undetectable level eliminates sexual transmission risk ("Undetectable=Untransmittable" or "U=U"). However, U=U messaging has been met with skepticism among sexual minority men (SMM) and others. In this survey-based experiment, we manipulated messaging about HIV risk and examined reactions and perceived message accuracy among US SMM.
Methods: SMM living with HIV (n = 106) and HIV-negative/status-unknown SMM (n = 351) participated in an online survey (2019-2020). Participants were randomly assigned to 1 of 3 messaging conditions, which varied by level of HIV sexual transmission risk associated with an undetectable viral load (No Risk [U=U]/Low Risk/Control). Participants reported reactions, message accuracy, and reasons for perceiving inaccuracy. We coded open-response data (reactions and reasons) into conceptual categories (eg, "Enthusiasm"). We compared reactions, accuracy ratings, and reasons by condition and serostatus.
Results: In the No Risk Condition, common reactions were Enthusiasm (40.0%), Skepticism/Disagreement (20.0%), and Agreement (19.4%), reactions common to comparison conditions. A higher percentage of HIV-negative/status-unknown participants (24.1%) expressed Skepticism/Disagreement in the No Risk Condition compared with other conditions (3.2%-9.7%). Participants living with HIV were more likely than HIV-negative/status-unknown participants to perceive the message as accurate in all conditions. In the No Risk Condition, common reasons for perceiving inaccuracy were Risk Misstated (46.1%), Oversimplified/Caveats Needed (17.1%), and Personal Unfamiliarity/Uncertainty (14.5%), reasons common to comparison conditions. Across conditions, 10.3% of participants attributed message inaccuracy to undetectable being misdefined.
Conclusion: Most SMM reacted favorably to U=U messaging. However, many-especially HIV-negative/status-unknown SMM-expressed skepticism. Interventions are needed to enhance U=U understanding and acceptance.
Competing Interests: The authors have no funding or conflicts of interest to disclose.
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Databáze: MEDLINE