Adherence to Mediterranean Diet and Diet Quality in Patients with Inflammatory Bowel Disease: A Single-Center, Observational, Case-Control Study.

Autor:	Cadoni M; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy.; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Favale A; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy.; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Piras R; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy., Demurtas M; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Soddu P; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy.; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Usai A; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy.; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Ibba I; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Fantini MC; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy.; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy., Onali S; Department of Medical Science and Public Health, University of Cagliari, 09124 Cagliari, Italy.; Azienda Ospedaliero-Universitaria di Cagliari, 09123 Cagliari, Italy.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2024 May 21; Vol. 16 (11). Date of Electronic Publication: 2024 May 21.
DOI:	10.3390/nu16111557
Abstrakt:	The nutritional status in inflammatory bowel disease (IBD) is often impaired, and adherence to the Mediterranean diet (MedDiet) remains under-investigated. The aim of this study was to assess diet quality (DQ) and adherence to MedDiet in a cohort of Sardinian IBD patients. We conducted a case-control study in which 50 Crohn's disease (CD) and 50 ulcerative colitis (UC) patients were matched with 100 healthy controls each. The Diet Quality Index (DQI-I) and Medi-Lite were used to assess DQ and adherence to MedDiet, respectively. Subgroup analysis by disease characteristics and use of advanced therapies were also carried out. DQI-I scored significantly lower in IBD, independently of disease localization and behavior (CD) and disease extent (UC): [DQI-I: CD 34.5 (IQR 33-37) vs. CTRL 40 (IQR 38.5-43) p < 0.0001; UC 34.5 (IQR 33-37) vs. CTRL 42 (IQR 40-44) p < 0.0001]. Medi-Lite scores were significantly lower in stricturing and ileo-colonic CD and in extensive UC: [Medi-Lite CD 7.5 (IQR 7-9)] vs. CTRL 9 (IQR 7-10) p = 0.0379]; [UC 8 (IQR7-10) vs. CTRL 9 (IQR 8-10.5) p = 0.0046]. IBD patients had a low DQ independently of disease type and phenotype. Patients with ileo-colonic stenosing CD or extensive UC had lower MedDiet adherence, suggesting that its benefits may be mitigated by low acceptance in specific subgroups.
Databáze:	MEDLINE
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