Dietary supplementation with black cricket (Gryllus assimilis) reverses protein-energy malnutrition and modulates renin-angiotensin system expression in adipose tissue.

Autor: Ribeiro GHM; Postgraduate Program in Food Science, Faculty of Food Engineering, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil; Institute of Agricultural Science, Postgraduate Program in Food and Health, University Federal of Minas Gerais (UFMG), Montes Claros, Minas Gerais, Brazil., Guimarães VHD; Postgraduate Program in Health Sciences, State University of Montes Claros (UNIMONTES), Montes Claros, Minas Gerais, Brazil., Teixeira HADS; Postgraduate Program in Biomedical Sciences, Italian University Institute of Rosario (IUNIR), Rosario, Santa Fe, Argentina., Farias LC; Postgraduate Program in Health Sciences, State University of Montes Claros (UNIMONTES), Montes Claros, Minas Gerais, Brazil., Guimarães ALS; Postgraduate Program in Health Sciences, State University of Montes Claros (UNIMONTES), Montes Claros, Minas Gerais, Brazil., de Paula AMB; Postgraduate Program in Health Sciences, State University of Montes Claros (UNIMONTES), Montes Claros, Minas Gerais, Brazil., Santos SHS; Institute of Agricultural Science, Postgraduate Program in Food and Health, University Federal of Minas Gerais (UFMG), Montes Claros, Minas Gerais, Brazil; Postgraduate Program in Health Sciences, State University of Montes Claros (UNIMONTES), Montes Claros, Minas Gerais, Brazil. Electronic address: sergiosousas@hotmail.com.
Jazyk: angličtina
Zdroj: Food research international (Ottawa, Ont.) [Food Res Int] 2024 Aug; Vol. 189, pp. 114570. Date of Electronic Publication: 2024 May 27.
DOI: 10.1016/j.foodres.2024.114570
Abstrakt: Edible insects are recognized as promising food sources due to their nutritional composition. Some species, such as Gryllus assimilis, contain proteins, lipids, and carbohydrates of high biological value, which regulate several metabolic functions, including the Renin-Angiotensin System (RAS). In this context, the present study aimed to assess the effects of dietary supplementation with whole Gryllus assimilis powder on the metabolism of malnourished mice. Thirty-two male Swiss mice were used and divided into four treatment groups. The groups were identified as (AIN93-M); AIN93-M + Gryllus assimilis diet (AIN93-M + GA); AIN93-M + Renutrition diet (AIN93-M + REN) and AIN93-M + Renutrition diet + Gryllus assimilis (AIN93-M + REN + GA). The results showed that whole Gryllus assimilis powder inclusion promotes recovery from protein-energy malnutrition, reduces adiposity, and improves glucose tolerance and insulin sensitivity. It also reduces total cholesterol, triglycerides, VLDL, and adipocyte area. We also observed a significant increase in the expression of RAS-related genes, such as ACE2 and MasR, followed by a reduction in Angiotensinogen and ACE. The main findings of the present study suggest the use of black cricket as a viable strategy for the prevention and treatment of protein-energy malnutrition, as well as the reduction of adiposity, and improvement of lipid and glycemic parameters, with antihypertensive potential.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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