An immersive virtual reality shopping task detects declines in instrumental activities of daily living in individuals with Parkinson's disease.

Autor: Rosenfeldt AB; Cleveland Clinic, Lerner Research Institute, Department of Biomedical Engineering, Cleveland, OH, USA., Waltz C; Cleveland Clinic, Lerner Research Institute, Department of Biomedical Engineering, Cleveland, OH, USA., Zimmerman E; Cleveland Clinic, Neurological Institute, Center for Neurological Restoration, Cleveland, OH, USA., Davidson S; Cleveland Clinic, Neurological Institute, Center for Neurological Restoration, Cleveland, OH, USA., Hastilow K; Cleveland Clinic, Lerner Research Institute, Department of Biomedical Engineering, Cleveland, OH, USA., Alberts JL; Cleveland Clinic, Lerner Research Institute, Department of Biomedical Engineering, Cleveland, OH, USA; Cleveland Clinic, Neurological Institute, Center for Neurological Restoration, Cleveland, OH, USA. Electronic address: albertj@ccf.org.
Jazyk: angličtina
Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2024 Aug; Vol. 125, pp. 107019. Date of Electronic Publication: 2024 May 28.
DOI: 10.1016/j.parkreldis.2024.107019
Abstrakt: Introduction: Declines in instrumental activities of daily living (IADLs) have been proposed as a prodromal marker of Parkinson's disease (PD). The Cleveland Clinic Virtual Reality Shopping (CC-VRS) platform combines an omnidirectional treadmill with a virtual reality headset to create a virtual grocery store that a user physically walks through and completes a shopping task. The primary aim of this project was to determine the known-group validity of the CC-VRS platform in discriminating IADL performance and to characterize specific motor and cognitive declines responsible for PD-related IADL impairments.
Methods: Sixteen individuals with PD and 15 healthy adults completed traditional motor, cognitive, and IADL assessments and the CC-VRS task. Group differences were evaluated using Welch's t-test.
Results: There were no between-group differences in traditional performance measures of motor, cognitive, or IADL function. Regarding CC-VRS performance, participants in the PD group completed the task significantly slower than controls (690 vs. 523 sec, respectively). Participants with PD spent 25 % more time walking and turning and were stopped 46 % longer than controls. Average gait speed when viewing the shopping list, a measure of dual-task performance, was significantly slower in the PD group compared to controls (0.26 vs. 0.17 m/s, respectively).
Conclusion: Unlike traditional performance measures of motor, cognitive, and IADL function, the CC-VRS discriminated participants with PD from healthy older adults. For the PD group, motor and dual-task declines contributed to diminished CC-VRS performance. Identifying underlying contributors to IADL declines supports using ecological assessments, such as the CC-VRS, for the routine clinical evaluation of IADLs.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Jay L. Alberts and Anson B. Rosenfeldt have authored intellectual property related to the CC-VRS platform.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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