A possible association between intraocular pressure changes and pigment epithelial detachment in central serous chorioretinopathy.

Autor: Balaratnasingam C; Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Western Australia, Australia.; Lions Eye Institute, Nedlands, Western Australia, Australia.; Retina Service, Department of Ophthalmology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia., Curcio CA; Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, Heersink School of Medicine, Birmingham, Alabama, USA., Morgan WH; Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Western Australia, Australia.; Lions Eye Institute, Nedlands, Western Australia, Australia.; Glaucoma Service, Department of Ophthalmology, Royal Perth Hospital, Perth, Western Australia, Australia., van Dijk EHC; Retina Service, Department of Ophthalmology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; Leiden University Medical Center, Department of Ophthalmology, Leiden, The Netherlands.
Jazyk: angličtina
Zdroj: Acta ophthalmologica [Acta Ophthalmol] 2024 Nov; Vol. 102 (7), pp. 843-848. Date of Electronic Publication: 2024 Jun 11.
DOI: 10.1111/aos.16730
Abstrakt: Central serous chorioretinopathy (CSC) is a frequently occurring chorioretinal disease, that is commonly associated with subretinal fluid accumulation in a generally young population. Even though choroidal abnormalities have been found to be of importance, the exact pathogenesis of CSC is still being learned. The origin of pigment epithelial detachments, seen in many CSC patients, is also unclear. Based on the follow-up of a CSC patient for more than 5 years, we hypothesize that intraocular pressure and, by extension, the pressure gradient across the Bruch's membrane, may be one factor in the pathogenesis of pigment epithelial detachments in CSC, which might very well have implications for the occurrence of and possible ways to prevent subretinal fluid in CSC.
(© 2024 The Author(s). Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation.)
Databáze: MEDLINE
Externí odkaz: