Microbiome and epigenetic variation in wild fish with low genetic diversity.

Autor: Anka IZ; Department of Biosciences, Centre for Sustainable Aquatic Research, Swansea University, Swansea, Wales, SA2 8PP, UK.; Department of Aquaculture, Chattogram Veterinary and Animal Sciences University, Chattogram, 4225, Bangladesh., Uren Webster TM; Department of Biosciences, Centre for Sustainable Aquatic Research, Swansea University, Swansea, Wales, SA2 8PP, UK., Berbel-Filho WM; Department of Biology, University of Oklahoma, Norman, OK, 73019, USA.; Department of Biology, University of West Florida, Pensacola, FL, USA., Hitchings M; Institute of Life Science, Swansea University, Swansea, Wales, SA2 8PP, UK., Overland B; Department of Biosciences, Centre for Sustainable Aquatic Research, Swansea University, Swansea, Wales, SA2 8PP, UK., Weller S; Department of Biosciences, Centre for Sustainable Aquatic Research, Swansea University, Swansea, Wales, SA2 8PP, UK., Garcia de Leaniz C; Department of Biosciences, Centre for Sustainable Aquatic Research, Swansea University, Swansea, Wales, SA2 8PP, UK.; Marine Research Centre (CIM-UVIGO), Universidade de Vigo, Vigo, Spain., Consuegra S; Department of Biosciences, Centre for Sustainable Aquatic Research, Swansea University, Swansea, Wales, SA2 8PP, UK. s.consuegra@swansea.ac.uk.; Grupo de Biotecnología Acuática, Departamento de Biotecnología y Acuicultura, Instituto de Investigacións Mariñas, IIM-CSIC, Vigo, Spain. s.consuegra@swansea.ac.uk.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2024 Jun 03; Vol. 15 (1), pp. 4725. Date of Electronic Publication: 2024 Jun 03.
DOI: 10.1038/s41467-024-49162-8
Abstrakt: Non-genetic sources of phenotypic variation, such as the epigenome and the microbiome, could be important contributors to adaptive variation for species with low genetic diversity. However, little is known about the complex interaction between these factors and the genetic diversity of the host, particularly in wild populations. Here, we examine the skin microbiome composition of two closely-related mangrove killifish species with different mating systems (self-fertilising and outcrossing) under sympatric and allopatric conditions. This allows us to partition the influence of the genotype and the environment on their microbiome and (previously described) epigenetic profiles. We find the diversity and community composition of the skin microbiome are strongly shaped by the environment and, to a lesser extent, by species-specific influences. Heterozygosity and microbiome alpha diversity, but not epigenetic variation, are associated with the fluctuating asymmetry of traits related to performance (vision) and behaviour (aggression). Our study identifies that a proportion of the epigenetic diversity and microbiome differentiation is unrelated to genetic variation, and we find evidence for an associative relationship between microbiome and epigenetic diversity in these wild populations. This suggests that both mechanisms could potentially contribute to variation in species with low genetic diversity.
(© 2024. The Author(s).)
Databáze: MEDLINE
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