Invited review: Impact of maternal health and nutrition on the microbiome and immune development of neonatal calves.
| Autor: | Diddeniya G; Faculty of Agriculture, University of Peradeniya, Kandy 20400, Sri Lanka., Hosseini Ghaffari M; Institute of Animal Science, Physiology Unit, University of Bonn, 53115 Bonn, Germany., Hernandez-Sanabria E; Department of Microbiology and Immunology, Laboratory of Molecular Bacteriology, Rega Institute, KU Leuven, Leuven 3000, Belgium., Guan LL; Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Malmuthuge N; Lethbridge Research and Development Center, Agriculture and Agri-Food Canada, Lethbridge, AB T1J 4B1, Canada. Electronic address: nilusha.malmuthuge@agr.gc.ca. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Journal of dairy science [J Dairy Sci] 2024 Oct; Vol. 107 (10), pp. 7504-7519. Date of Electronic Publication: 2024 May 31. |
| DOI: | 10.3168/jds.2024-24835 |
| Abstrakt: | This comprehensive review highlights the intricate interplay between maternal factors and the co-development of the microbiome and immune system in neonatal calves. Based on human and mouse studies, multiple prenatal and postnatal factors influence this process by altering the host-associated microbiomes (gut, respiratory tract, skin), microbial colonization trajectories, and priming of the immune systems (mucosal and systemic). This review emphasizes the importance of early-life exposure, highlighting postnatal factors that work in synergy with maternal factors in further fine-tuning the co-development of the neonatal microbiome and immunity. In cattle, there is a general lack of research to identify the maternal effect on the early colonization process of neonatal calves (gut, respiratory tract) and its impact on the priming of the immune system. Past studies have primarily investigated maternal effects on the passive transfer of immunity at birth. The co-development process of the microbiome and immune system is vital for lifelong health and production in cattle. Therefore, comprehensive research beyond the traditional focus on passive immunity is an essential step in this endeavor. Calf microbiome research reports the colonization of diverse bacterial communities in newborns, which is affected by the colostrum feeding method immediately after birth. In contrast to human studies reporting a strong link between maternal and infant bacterial communities, there is a lack of evidence to clearly define cow-to-calf transmission in cattle. Maternal exposure has been shown to promote the colonization of beneficial bacteria in neonatal calves. Nonetheless, calf microbiome research lacks links to early development of the immune system. An in-depth understanding of the influence of maternal factors on microbiomes and immunity will improve the management of pregnant cows to raise immune-fit neonatal calves. It is essential to investigate the diverse effects of maternal health conditions and nutrition during pregnancy on the gut microbiome and immunity of neonatal calves through collaboration among researchers from diverse fields such as microbiology, immunology, nutrition, veterinary science, and epidemiology. (Copyright © 2024 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|