Mechanistic study on the increase of Microcystin-LR synthesis and release in Microcystis aeruginosa by amino-modified nano-plastics.

Autor: Huang J; Institute of Environmental Processes and Pollution Control, Jiangnan University, Wuxi 214122, PR China; School of Environment and Ecology, Jiangnan University, Wuxi 214122, PR China., Gu P; Institute of Environmental Processes and Pollution Control, Jiangnan University, Wuxi 214122, PR China; School of Environment and Ecology, Jiangnan University, Wuxi 214122, PR China; Taihu Water Environment Research Center, Changzhou 213169, PR China., Cao X; Institute of Environmental Processes and Pollution Control, Jiangnan University, Wuxi 214122, PR China; School of Environment and Ecology, Jiangnan University, Wuxi 214122, PR China., Miao H; Institute of Environmental Processes and Pollution Control, Jiangnan University, Wuxi 214122, PR China; School of Environment and Ecology, Jiangnan University, Wuxi 214122, PR China; Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment, Suzhou University of Science and Technology, Suzhou 215009, PR China. Electronic address: hfmiao@jiangnan.edu.cn., Wang Z; Institute of Environmental Processes and Pollution Control, Jiangnan University, Wuxi 214122, PR China; School of Environment and Ecology, Jiangnan University, Wuxi 214122, PR China; Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment, Suzhou University of Science and Technology, Suzhou 215009, PR China.
Jazyk: angličtina
Zdroj: Journal of hazardous materials [J Hazard Mater] 2024 Aug 05; Vol. 474, pp. 134767. Date of Electronic Publication: 2024 May 29.
DOI: 10.1016/j.jhazmat.2024.134767
Abstrakt: Ecological risk of micro/nano-plastics (MPs/NPs) has become an important environmental issue. Microcystin-leucine-arginine (MC-LR) produced by Microcystis aeruginosa (M. aeruginosa) is the most common and toxic secondary metabolites (SM). However, the influencing mechanism of MPs and NPs exposure on MC-LR synthesis and release have still not been clearly evaluated. In this work, under both acute (4d) and long-term exposure (10d), only high-concentration (10 mg/L) exposure of amino-modified polystyrene NPs (PS-NH 2 -NPs) promoted MC-LR synthesis (32.94 % and 42.42 %) and release (27.35 % and 31.52 %), respectively. Mechanistically, PS-NH 2 -NPs inhibited algae cell density, interrupted pigment synthesis, weakened photosynthesis efficiency, and induced oxidative stress, with subsequent enhancing the MC-LR synthesis. Additionally, PS-NH 2 -NPs exposure up-regulated MC-LR synthesis pathway genes (mcyA, mcyB, mcyD, and mcyG) combined with significantly increased metabolomics (Leucine and Arginine), thereby enhancing MC-LR synthesis. PS-NH 2 -NPs exposure enhanced the MC-LR release from M. aeruginosa via up-regulated MC-LR transport pathway genes (mcyH) and the shrinkage of plasma membrane. Our results provide new insights into the long-time coexistence of NPs with algae in freshwater systems might pose a potential threat to aquatic environments and human health.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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