A Novel Score for an Old Enemy: Atherogenic Plasma Index Predicts In-Stent Restenosis among Stable Angina Pectoris Patients.

Autor:	Ser OS; Department of Cardiology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Türkiye., Sigirci S; Department of Cardiology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye., Keskin K; Department of Cardiology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye., Cetinkal G; Department of Cardiology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Türkiye., Kocas BB; Department of Cardiology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Türkiye., Kilci H; Department of Cardiology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye., Dalgic Y; Department of Cardiology, Derince Training and Research Hospital, Kocaeli, Türkiye., Kalender E; Department of Cardiology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye., Kilickesmez K; Department of Cardiology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Türkiye.
Jazyk:	angličtina
Zdroj:	Sisli Etfal Hastanesi tip bulteni [Sisli Etfal Hastan Tip Bul] 2024 Apr 05; Vol. 58 (1), pp. 75-81. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).
DOI:	10.14744/SEMB.2024.40336
Abstrakt:	Objectives: Although the association of Atherogenic index of plasma (AIP) with coronary artery disease (CAD) and atherosclerosis is known, the relationship between AIP and in-stent restenosis (ISR) remains unclear. We aimed to investigate the relationship between AIP and ISR in patients with stable angina pectoris (SAP) treated with drug-eluting stent (DES). Methods: Patients with a history of DES implantation following stable angina were evaluated between January 2015 and November 2019 in this observational and retrospective study. 608 eligible patients were dichotomized into ISR+ (n=241) and ISR- (n=367). ISR was defined as the presence of 50% or greater stenosis. AIP was defined as log [TG/HDL-C]. Results: AIP levels were significantly higher in patients who developed ISR compared with those who did not (0.33 [0.15-0.52] vs 0.06 [-0.08-0.21] respectively, p<0.001). The AUC value of AIP levels for predicting ISR was 0.746 (p<0.001). Multivariate logistic regression analysis revealed that AIP, diabetes mellitus, higher LDL-C levels and lower LVEF values were independently associated with ISR. Conclusion: Multivariate analysis revealed that AIP was strongly independently associated with ISR. Using this novel inexpensive and easily calculable index may provide early recognition of ISR in patients with SAP who were treated with DES. Competing Interests: None declared. (© Copyright 2024 by The Medical Bulletin of Sisli Etfal Hospital.)
Databáze:	MEDLINE
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