Toxoplasma gondii infection in European brown hares (Lepus europaeus) in Brazil.

Autor: Arias-Pacheco C; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., Perin PP; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., de Oliveira Andrade L; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., Gomes JS; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., Oliveira WJ; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., Mendonça TO; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., de Oliveira Zolla N; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil., Cavallieri AC; Laboratory of Protozoology, Preventive Veterinary Medicine Department, State University of Londrina, São Paulo, PR, 86057-970, Brazil., da Silva DA; Laboratory of Protozoology, Preventive Veterinary Medicine Department, State University of Londrina, São Paulo, PR, 86057-970, Brazil., Castilho PM; Laboratory of Protozoology, Preventive Veterinary Medicine Department, State University of Londrina, São Paulo, PR, 86057-970, Brazil., de Barros LD; Laboratory of Veterinary Parasitology and Parasitic Diseases, Veterinary Medicine Department, Federal University of Lavras, Londrina, MG, 37203-202, Brazil., Garcia JL; Laboratory of Protozoology, Preventive Veterinary Medicine Department, State University of Londrina, São Paulo, PR, 86057-970, Brazil., Lux Hoppe EG; Parasitic Diseases Laboratory (LabEPar), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinary Sciences, São Paulo State University, São Paulo, 14884-900, Brazil. lux.hoppe@unesp.br.
Jazyk: angličtina
Zdroj: Parasitology research [Parasitol Res] 2024 May 27; Vol. 123 (5), pp. 222. Date of Electronic Publication: 2024 May 27.
DOI: 10.1007/s00436-024-08248-4
Abstrakt: Toxoplasmosis is a worldwide zoonosis that affects warm-blooded animals, including humans. Wild animals can act as intermediate hosts of this pathogen; thus, this study aims to detect Toxoplasma gondii infection in invasive European brown hares in Brazil. For this, 72 wild European brown hares were captured from July 2020 to June 2022 in three Brazilian states: São Paulo, Paraná, and Rio Grande do Sul. The diagnostic of Toxoplasma gondii infection was performed by bioassay in mouse, histopathology in Hematoxylin-Eosin-stained tissue sections (brain, liver, lungs, kidneys, and small intestine), serology by IFAT, and molecular techniques by conventional PCR and qPCR. The combined prevalence of the different diagnostic methods was 51.4% (37/72, CI= 40.1 - 62.6 %), and there was no statistical difference between sexes, age range, or geographical region of the hosts. Mouse bioassay was the technique that detected more positive hares. To our knowledge, this is the first confirmation of Toxoplasma gondii infection in invasive European brown hares in Brazil. These animals act as reservoirs and potential infection source for carnivores and other wild and domestic animals, including humans, thus contributing to perpetuate the disease cycle in São Paulo, Paraná, and Rio Grande do Sul States. Research such as the present study is necessary to raise awareness about the role of animals in the disease cycle.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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