| Autor: |
Aredo JV; Rehabilitation Medicine Department, Intramural Research Program, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Medicine, University of California, San Francisco, CA 94143, USA., Tandon HK; Rehabilitation Medicine Department, Intramural Research Program, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Internal Medicine and Geriatrics, Oregon Health and Science University, Portland, OR 97239, USA., Panahi S; Department of Family Science, School of Public Health, University of Maryland, College Park, MD 20742, USA., Phan VT; Rehabilitation Medicine Department, Intramural Research Program, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.; School of Medicine, Georgetown University, Washington, DC 20007, USA., Ameli R; NIMH Representative to the Clinical Center Pain and Palliative Care Service, National Institutes of Health, Bethesda, MD 20892, USA., Karp BI; Office of the Clinical Director, Intramural Research Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Stratton P; Office of the Clinical Director, Intramural Research Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. |
| Abstrakt: |
Botulinum toxin (BoNT) injection can safely be done as an office-based procedure, but can be painful itself, especially when injecting pelvic floor muscles to treat chronic pelvic pain (CPP). Mindfulness interventions may reduce procedure-associated acute anxiety and pain. We applied mindfulness techniques to increase the tolerability of office-based pelvic floor BoNT injections in women with CPP. Women enrolled in a clinical trial of BoNT for endometriosis-associated CPP were offered a brief, guided mindfulness session before and/or after transvaginal injection. Anxiety, pain, and dysphoria were rated on a 0-10 numerical rating scale (NRS) before and after each mindfulness session. Eight women underwent mindfulness sessions. Five participants had a session before and two after the transvaginal injection. One participant had two sessions: one before and one after separate injections. All six women completing a session prior to injection had at least moderate anxiety, which lessened after the mindfulness session (median NRS change: -3.3/10). All three women reporting injection-associated pain experienced less intense pain following the post-injection session (median NRS change: -3/10). Three women experiencing dysphoria improved after the session (median NRS change: -3/10). A brief, guided mindfulness session may lessen acute pain, anxiety, and dysphoria associated with office-based transvaginal BoNT injection. |
