Dentate nucleus: a review and implications for dentatotomy.

Autor: Rios-Zermeno J; Department of Neurosurgery, Instituto Nacional de Neurologia y Neurocirugia, Av Insurgentes Sur 3877, Tlalpan, Mexico City, Mexico., Ballesteros-Herrera D; Department of Neurosurgery, Instituto Nacional de Neurologia y Neurocirugia, Av Insurgentes Sur 3877, Tlalpan, Mexico City, Mexico., Dominguez-Vizcayno P; Department of Radioneurosurgery, Instituto Nacional de Neurologia y Neurocirugia, Mexico City, Mexico., Carrillo-Ruiz JD; Research Direction & Stereotactic and Functional Neurosurgery, Mexico General Hospital, Mexico City, Mexico.; Neuroscience CoordinationPschycology Faculty, Mexico Anahuac University, Mexico City, Mexico., Moreno-Jimenez S; Department of Neurosurgery, Instituto Nacional de Neurologia y Neurocirugia, Av Insurgentes Sur 3877, Tlalpan, Mexico City, Mexico. smoreno@innn.edu.mx.; Neurological Center, American British Cowdray Medical Center, Mexico City, Mexico. smoreno@innn.edu.mx.
Jazyk: angličtina
Zdroj: Acta neurochirurgica [Acta Neurochir (Wien)] 2024 May 17; Vol. 166 (1), pp. 219. Date of Electronic Publication: 2024 May 17.
DOI: 10.1007/s00701-024-06104-z
Abstrakt: Purpose: The dentate nucleus (DN) is the largest, most lateral, and phylogenetically most recent of the deep cerebellar nuclei. Its pivotal role encompasses the planning, initiation, and modification of voluntary movement but also spans non-motor functions like executive functioning, visuospatial processing, and linguistic abilities. This review aims to offer a comprehensive description of the DN, detailing its embryology, anatomy, physiology, and clinical relevance, alongside an analysis of dentatotomy.
Methods and Results: We delve into the history, embryology, anatomy, vascular supply, imaging characteristics, and clinical significance of the DN. Furthermore, we thoroughly review the dentatotomy, emphasizing its role in treating spasticity.
Conclusions: Understanding the intricacies of the anatomy, physiology, vasculature, and projections of the DN has taken on increased importance in current neurosurgical practice. Advances in technology have unveiled previously unknown functions of the deep cerebellar nuclei, predominantly related to non-motor domains. Such discoveries are revitalizing older techniques, like dentatotomy, and applying them to newer, more localized targets.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)
Databáze: MEDLINE
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