Varicella zoster virus outbreak in a long-term care unit of a tertiary care hospital in northern India.

Autor:	Saksena R; Department of Microbiology, VMMC and Safdarjung Hospital, New Delhi, India., Thomas BJ; Department of Microbiology, VMMC and Safdarjung Hospital, New Delhi, India., Das R; Department of Microbiology, AIIMS, New Delhi, India., Nagpal S; Department of Microbiology, VMMC and Safdarjung Hospital, New Delhi, India., Suri PR; Department of Microbiology, VMMC and Safdarjung Hospital, New Delhi, India., Wadhwa RK; Department of Physical Medicine and Rehabilitation, VMMC and Safdarjung Hospital, New Delhi, India., Choudhary A; Department of Microbiology, AIIMS, New Delhi, India., Gaind R; Department of Microbiology, VMMC and Safdarjung Hospital, New Delhi, India., Gupta E; Department of Virology, ILBS, New Delhi, India.
Jazyk:	angličtina
Zdroj:	Epidemiology and infection [Epidemiol Infect] 2024 May 13; Vol. 152, pp. e81. Date of Electronic Publication: 2024 May 13.
DOI:	10.1017/S0950268824000712
Abstrakt:	Nosocomial outbreak of varicella zoster virus (VZV) has been reported when susceptible individuals encounter a case of chicken pox or shingles. A suspected VZV outbreak was investigated in a 50-bedded in-patient facility of Physical Medicine and Rehabilitation in a tertiary care multispecialty hospital. A 30-year-old female patient admitted with Pott's spine was clinically diagnosed with chicken pox on 31 December 2022. The following week, four more cases were identified in the same ward. All cases were diagnosed as laboratory-confirmed varicella zoster infection by PCR. Primary case was a housekeeping staff who was clinically diagnosed with chicken pox 3 weeks prior (9 December 2022). He returned to work on eighth day of infection (17 December 2022) after apparent clinical recovery but before the lesions had crusted over. Thirty-one HCWs were identified as contacts a and three had no evidence of immunity. Two of these susceptible HCWs had onset of chickenpox shortly after first dose of VZV vaccination was inoculated. All cases recovered after treatment with no reported complications. VZV infection is highly contagious in healthcare settings with susceptible populations. Prompt identification of cases and implementation of infection prevention and control measures like patient isolation and vaccination are essential for the containment of outbreaks.
Databáze:	MEDLINE
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