Interstitial lung disease: a review of classification, etiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment.

Autor:	Althobiani MA; Royal Free Campus, UCL Respiratory, University College London, London, United Kingdom.; Department of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia., Russell AM; School of Health and Care Professions, University of Exeter, Exeter, United Kingdom.; School of Medicine and Health, University of Birmingham, Birmingham, United Kingdom., Jacob J; UCL Respiratory, University College London, London, United Kingdom.; Satsuma Lab, Centre for Medical Image Computing, University College London Respiratory, University College London, London, United Kingdom., Ranjan Y; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Folarin AA; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust, King's College London, London, United Kingdom.; Institute of Health Informatics, University College London, London, United Kingdom.; NIHR Biomedical Research Centre at University College London Hospitals, NHS Foundation Trust, London, United Kingdom., Hurst JR; Royal Free Campus, UCL Respiratory, University College London, London, United Kingdom., Porter JC; UCL Respiratory, University College London, London, United Kingdom.
Jazyk:	angličtina
Zdroj:	Frontiers in medicine [Front Med (Lausanne)] 2024 Apr 18; Vol. 11, pp. 1296890. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024).
DOI:	10.3389/fmed.2024.1296890
Abstrakt:	Interstitial lung diseases (ILDs) refer to a heterogeneous and complex group of conditions characterized by inflammation, fibrosis, or both, in the interstitium of the lungs. This results in impaired gas exchange, leading to a worsening of respiratory symptoms and a decline in lung function. While the etiology of some ILDs is unclear, most cases can be traced back to factors such as genetic predispositions, environmental exposures (including allergens, toxins, and air pollution), underlying autoimmune diseases, or the use of certain medications. There has been an increase in research and evidence aimed at identifying etiology, understanding epidemiology, improving clinical diagnosis, and developing both pharmacological and non-pharmacological treatments. This review provides a comprehensive overview of the current state of knowledge in the field of interstitial lung diseases. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Althobiani, Russell, Jacob, Ranjan, Folarin, Hurst and Porter.)
Databáze:	MEDLINE
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