Euphoric Presentation in Creutzfeldt-Jakob Disease and Its Diagnostic Implications: A Case Report.

Autor: Sahyouni M; Internal Medicine, Campbell University School of Osteopathic Medicine, Buies Creek, USA.; Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA., Casey B 3rd; Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA., Carpenter Z; Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA., Estrella F; Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA., Okafor C; Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Apr 01; Vol. 16 (4), pp. e57419. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
DOI: 10.7759/cureus.57419
Abstrakt: Creutzfeldt-Jakob disease (CJD) constitutes an aggressively advancing, terminal neurodegenerative condition classified within the spectrum of transmissible spongiform encephalopathies. The difficulty in establishing a diagnosis before death arises from the condition's rarity and the resulting limited level of suspicion attributed to it. The polymorphic nature of CJD symptoms contributes to the challenge of early diagnostic recognition. Emotional and behavioral changes have been well documented, but the initial presentation of euphoria has not been documented. Here, we present the case of a female patient who was experiencing an unusual state of euphoria followed by intermittently altered mental status. She was ultimately diagnosed with sporadic CJD, discharged home on hospice, and died within six months of discharge.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Sahyouni et al.)
Databáze: MEDLINE