| Autor: |
Taylor A; Department of Paediatrics, The University of Auckland, Auckland, New Zealand., Neutze J; Kidz First Children's Hospital, Te Whatu Ora Counties Manukau, Auckland, New Zealand., Moreland NJ; Department of Molecular Medicine and Pathology, The University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand., Webb R; Department of Paediatrics, The University of Auckland, Auckland, New Zealand.; Kidz First Children's Hospital, Te Whatu Ora Counties Manukau, Auckland, New Zealand.; Starship Children's Health, Te Whatu Ora Te Toka Tumai Auckland, Auckland, New Zealand. |
| Abstrakt: |
The COVID-19 pandemic has altered the epidemiology of many common childhood infections, including Group A streptococcal (GAS) disease. Acute post-streptococcal glomerulonephritis (APSGN) is a nonsuppurative complication of GAS pharyngitis and pyoderma. It remains the most common cause of pediatric acute glomerulonephritis globally. In Counties Manukau, New Zealand, APSGN rates have previously been shown to be the highest in the country, with marked ethnic and socioeconomic disparities. We performed a retrospective review of children aged 0-14 years who were discharged from Kidz First Hospital, Counties Manukau, between 2015 and 2023 and met the Strep A Vaccine Global Consortium consensus definition of APSGN. We describe a marked, sustained reduction in APSGN hospitalizations, temporally associated with the COVID-19 pandemic. This ongoing reduction in APSGN incidence is notable in light of contrasting reports of increasing incidence of rheumatic fever in New Zealand and invasive GAS disease internationally. |
