Onychoscopic Analysis of Cyclophosphamide-Induced Polydactylic Bluish-Gray Discoloration in a Case of Pemphigus Foliaceus.

Autor: Garg P; Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND., Mundhe AD; Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND., Jadhav A; Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND., Mishra N; Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND., Deo KS; Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Mar 30; Vol. 16 (3), pp. e57233. Date of Electronic Publication: 2024 Mar 30 (Print Publication: 2024).
DOI: 10.7759/cureus.57233
Abstrakt: Cyclophosphamide, an alkylating agent, has rarely been observed to cause a bluish discoloration of nails, an occurrence that is typically underreported. We describe the case of a middle-aged male undergoing dexamethasone-cyclophosphamide pulse therapy for pemphigus foliaceus, who exhibited bluish-gray discoloration of the nails. It is crucial to differentiate this presentation from other conditions such as nail apparatus melanoma (NAM), which may manifest in a slightly different manner. We also report the onychoscopic findings observed in this case.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Garg et al.)
Databáze: MEDLINE