| Autor: |
Moraes DMC; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil., Almeida AMS; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil., Andrade MA; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil., Nascente EP; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil., Duarte SC; Brazilian Agricultural Research Corporation (Embrapa), Brasília 70770-901, Brazil., Nunes IA; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil., Jayme VS; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil., Minafra C; Department of Veterinary Medicine, Federal University of Goiás, Goiania 74605-080, Goiás, Brazil.; Center for Food Research, Federal University of Goiás, Goiania 74660-970, Goiás, Brazil. |
| Abstrakt: |
Microbial resistance to antibiotics poses a significant threat to both human and animal health, necessitating international efforts to mitigate this issue. This study aimed to assess the resistance profiles of Salmonella sp. isolates and identify the presence of intl 1, sul 1, and bla TEM resistance genes within antigenically characterized isolates, including Agona, Livingstone, Cerro, Schwarzengrund, Salmonella enterica subsp. enterica serotype O:4.5, Anatum, Enteritidis, Johannesburg, Corvallis, and Senftenberg. These isolates underwent susceptibility testing against 14 antibiotics. The highest resistance percentages were noted for sulfamethoxazole (91%), sulfonamides (51%), and ceftiofur (28.9%), while no resistance was observed for ciprofloxacin. Salmonella Johannesburg and Salmonella Corvallis showed resistance to one antibiotic, whereas other serovars were resistant to at least two. Salmonella Schwarzengrund exhibited resistance to 13 antibiotics. The intl 1 gene was detected in six out of the ten serovars, and the sul 1 gene in three, always co-occurring with intl 1. The bla TEM gene was not identified. Our findings highlight the risk posed by the detected multiple resistances and genes to animal, human, and environmental health. The multidrug resistance, especially to third-generation cephalosporins and fluoroquinolones, highlights the need for stringent monitoring of Salmonella in laying hens. The potential of the environment, humans, eggs, and their products to act as vectors for antibiotic resistance represents a significant concern for One Health. |
